Results 171 to 180 of about 49,334 (344)

Structural Analysis of Factors Influencing the Resilience of the Hospital Medical Equipment Supply Chain Using Fuzzy MICMAC

open access: yesبیمارستان
Background and purpose: The complexity and extreme fluctuations in the healthcare environment, along with the occurrence of unforeseen disasters and risks, have increased the likelihood of disruptions in hospital supply chains. Strengthening supply chain resilience is a key strategy to mitigate these challenges and ensure the continued delivery of ...
farokhlegha mohammadi   +2 more
openaire   +1 more source

Challenges Faced by Nurses while Caring for Preterm Babies in the Newborn Unit at Kisii Teaching and Referral Hospital

open access: yes, 2020
Preterm birth is a global problem with the greatest burden experienced in sub-Saharan Africa and South Asia. In Kenya, 193,000 babies are born too soon each year and 9,670 children under five die due to direct preterm complications.
Kereri, Deborah   +2 more
core  

Selective Inhibition of Integrin β3 Topology Provides a Safer Antithrombotic Strategy

open access: yesAdvanced Science, EarlyView.
Current integrin αIIbβ3 inhibitors effectively reduce thrombosis but also increase bleeding risk. During thrombosis, high shear blood flow can directly activate the integrin αIIbβ3 via a distinct topological change in the β3 transmembrane domain, independent of hemostatic platelet signaling.
Joonha Lee   +11 more
wiley   +1 more source

Control technology for ethylene oxide sterilization in hospitals [PDF]

open access: yes
"The relative importance of various ethylene-oxide (75218) (EtO) emission sources associated with gas sterilizers was assessed and the effectiveness of certain control measures on limiting health care worker exposure to EtO was determined.

core  

Aptamer‐Engineered Liposomal Platform Enables in Situ cDC1 Vaccination to Potentiate Immunotherapy in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang   +8 more
wiley   +1 more source

Registered Nurse Perspectives on Delayed or Missed Nursing Cares in a New Zealand Hospital

open access: yes, 2012
Nurses have an essential role to play in ongoing patient surveillance. The quality of nursing care patients receive has implications for both their recovery and long term health outcomes.
Stephen Neville, Rosie Winters
core  

Targeting Supramolecular Active Complexes of Nav1.7/Nav1.8 to Relieve Chronic Neuropathic Pain

open access: yesAdvanced Science, EarlyView.
In mice and patients with severe chronic neuropathic pain (NP), Nav1.7, Nav1.8, TrkB, and five cytoskeletal proteins form supramolecular active complexes (SMACs) with polygonal lattice structures as noxious signal amplifiers in dorsal root ganglion (DRG) neurons.
Liting Sun   +27 more
wiley   +1 more source

Bifidobacterium Pseudolongum‐Derived Inosine Mitigates Polystyrene Nanoplastics‐Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages

open access: yesAdvanced Science, EarlyView.
Probiotic B.p colonization elevated gut‐derived inosine level in the liver, while elevated inosine activated A2AR and subsequently blocked NPs‐induced polarization of M1 macrophages by repressing the miR155/SOCS1/NF‐κB pathway. This reduced the release of inflammatory cytokines and thereby, mitigated NPs‐induced hepatic injury.
Kaikai Zhang   +10 more
wiley   +1 more source

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