Results 231 to 240 of about 48,752 (298)

Reimagining the Community Nursing Bag: Eco-Smart and Technology-Integrated Solutions. [PDF]

Cureus
Niranjani S, Krishnan P, Umadevi T, N J.
europepmc   +1 more source

Dual pKa Lipid Nanoparticles for Lung‐tropic mRNA Delivery and pH‐Programmed Endosomal Escape

Advanced Science, EarlyView.
Lipid nanoparticles’ bottleneck lies in low endosomal escape efficiency and liver‐dominant delivery after intravenous administration. To overcome these limitations, we present a stepwise pH‐programmed lipid nanoparticle system enabled by our newly synthesized ionizable lipid.
Seong Gi Lim, Minju Lee, Yiming Wang, Eunjin Choi, Ji Sun Park, Kyungmin Park, Hayoung Jeon, Donghyun Kim, Donghyun Lee, Yeeun Lee, Kee‐Pyo Kim, Eunha Kim, Heebeom Koo   +12 more
wiley   +1 more source

Review and assessment of policies and practices for spinal cord injury-related health care supplies, services, and mobility equipment reveal wide inequities and inadequacies in Canada. [PDF]

Front Public Health
Warkentin PB, Gregory JH, Athanasopoulos P, Ripat J, Cowley KC.   +4 more
europepmc   +1 more source

Structural Basis of Shiga Toxin Neutralization by Human Antibodies Targeting Canonical Receptor‐Binding and Non‐Canonical Assembly Sites

Advanced Science, EarlyView.
Cryo‐electron microscopy structures reveal two distinct neutralization mechanisms of fully human monoclonal antibodies targeting the Shiga toxin 1a B subunit. RDS059 occludes the Gb3 receptor‐binding site, whereas RDS045 engages a lateral quaternary epitope to disrupt holotoxin assembly.
Jianting Ke, Xin Li, Xiaoli Wang, Zhaoxia Huang, Shaojie Xue, Yuyang Liu, Jing Pan, Guowei Hu, Yayu Wang, Cheng Wang, Shoudeng Chen   +10 more
wiley   +1 more source

Why vaccination should be a top priority in relief efforts after Venezuela's earthquake doublet. [PDF]

IJID Reg
Rodríguez-Morales AJ, Ulloa-Gutierrez R, Beltrán-Arroyave C, Risquez A, Hernandez MJ.   +4 more
europepmc   +1 more source

The Cancer Cell Metabolic Reprogramming Remodels the Tumor Microenvironment: Molecular Mechanisms and Therapeutic Strategies

Advanced Science, EarlyView.
This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang, Zhicheng Zhou, Xue Jiang, Zhenguang Du, Yangyang Zhan, Xinli Liu   +5 more
wiley   +1 more source

Improving Compliance With Surgical Scrubbing and Sterilization Protocols: A Two-Cycle Quality Improvement Project at Atbara Teaching Hospital. [PDF]

Cureus
Osman AMM, Mustafa SMB, Mahmoud AAO, Kubashi BMS, Ahmed MAY, Mohamed AMA, Mohamed Badawy ME, Mustafa AAG, Jadalla AAA, Ahmed HAS, Mohamed HHA, Zeinalabedeen LAA, Wahab MNM, Ahmed M, Mohammed AAO, Nassour ABA, Osman AIM, Ibrahim AEM.   +17 more
europepmc   +1 more source

Gaza: not to act is to act. [PDF]

Transpl Int
Mamode N, Fernandez-Diaz S, Tubail R, Masoud K, Masoud W.   +4 more
europepmc   +1 more source

Cost and clinical outcomes of epilepsy surgery in a Brazilian public hospital: a health economic evaluation. [PDF]

Arq Neuropsiquiatr
Rodrigues RMC, Bastos TTR, Moreira LCA, Fonseca VM, Landeiro JA, Pessôa BL.   +5 more
europepmc   +1 more source

Summary and Critical Appraisal of Evidence for Intrahospital Neonatal Transport. [PDF]

Pediatric Health Med Ther
Li X, Suo T, Zhang F, Wang L.
europepmc   +1 more source