Results 251 to 260 of about 49,334 (344)

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

The RNA‐Binding Protein PARN Remodeled 3′ UTR Structure Defines Poly(A)‐Loading Sites to Mediate Immunoglobulin Homeostasis

Advanced Science, EarlyView.
ABSTRACT Class Switch Recombination (CSR) is essential for generating high‐affinity antibody isotypes from IgM during adaptive humoral responses. Despite well‐established roles for various transcription factors, whether CSR is subject to dedicated post‐transcriptional control represents a significant gap in knowledge.
Siyuan Sun, Chen Yang, Xiaoyu Wang, Naijing Hu, Shengyao Zhang, Xinchun Li, Yu Chen, Jianan Zhai, Xiangfeng Tang, Wei Lu, Chenxu Lu, Changchang Cao, Weiru Yu, Wenhao Wu, Xiaonan Nie, Fengchao Wang, Bing Fang, Fazheng Ren, Yixuan Li, Juan Chen   +19 more
wiley   +1 more source

A Plug‐and‐Play Platform for Customizing Multivalent Degraders and Degrader‐Drug Conjugates

Advanced Science, EarlyView.
Membrane proteins remain challenging targets for conventional TPD approaches. Here, the authors develop UPTAB, a modular platform leveraging ultrahigh‐affinity orthogonal Im/CL protein pairs for lysosomal degradation of membrane proteins. Mono‐targeted (Type‐I), dual‐targeted (Type‐II), and tri‐targeted (Type‐III) UPTABs enable simultaneous degradation
Mengqing Zhao, Yan Deng, Jianjian Han, Yong Xie, Kai Bao, Lixin Ma, Lilong Liu, Wuxiang Mao   +7 more
wiley   +1 more source

Level of Emergency Preparedness and Associated Barriers at the Accident and Emergency Ward of a LMIC Hospital: A Cross-Sectional Assessment Using the WHO HEAT Tool. [PDF]

Open Access Emerg Med
Nabeshya J, Atiang E, Kwarikunda C, Luwaga R, Niyonzima V.   +4 more
europepmc   +1 more source

Toward Long‐Term Reliable Human‐Machine Interaction: A Flexible, Breathable, and Self‐Powered Pressure Sensor System With Firefighting Validation

Advanced Science, EarlyView.
This work develops a breathable potentiometric self‐powered pressure sensor with good wearability, using a non‐woven fabric substrate and hydrogel electrolyte. The sensor is integrated into a five‐channel smart glove to acquire reliable hand motion signals, which are processed by a CNN for identity verification and smart vehicle control in human ...
Qilong Zhang, Zhao Yao, Jiaxu Liu, Yuxuan Hou, Zhongtao Zhang, Jingwei Xue, Leonid Chernogor, Nam Young Kim, Eun Seong Kim, Yuanyue Li, Yang Li   +10 more
wiley   +1 more source

Comparative Cost Analysis of Ambulance Utilization: Advanced Life Support (ALS) vs Basic Life Support (BLS) at King Abdulaziz Medical City, Riyadh. [PDF]

Clinicoecon Outcomes Res
Alabdali A, Alharkan M.
europepmc   +1 more source

Drop‐Shaped Optical Microfiber Enabled Biomechanical Sensor

Advanced Science, EarlyView.
A novel microforce sensor based on a drop‐shaped optical microfiber is presented herein, designed to characterize the biomechanical properties of single cells and microscale living organisms, achieving a force resolution of 24 nN. Leveraging its high sensitivity, facile miniaturization, excellent flexibility, and robust mechanical stability, this ...
Yan Xu, Xitao Tu, Haochen Jiang, Jun Mo, Xinyue Zhang, Xiaomin Yue, Limin Tong, Lei Zhang   +7 more
wiley   +1 more source

Rebuilding Gaza's health system: A qualitative study of healthcare workers' experiences and lessons learned from responding to mass casualty incidents (2018-2021). [PDF]

PLoS One
Ismail A, Salah M, Gilbert M, Abu Alreesh YH, Jones C.   +4 more
europepmc   +1 more source

Correction: The Children’s Hospitals in Africa Mapping Project (CHAMP) survey: Facilities, equipment, supplies, infrastructure, and capacity to respond to emergencies

PLOS Global Public Health
Bhardwaj, Vinayak, Stanberry, Lawrence R., LaRussa, Philip, James, Wilmot, Mahida, Maitry, Kanyamuhunga, Aimable, Tekleab, Atnafu Mekonnen, Omoigberale, Augustine, Ngwenya, Crispen, Musorewegomo, David, Joel, Dipesalema, Mupere, Ezekiel, Eki-Udoko, Fidelis Ewenitie, Bousquet, Hannah, Buys, Heloise, Mujuru, Hilda Angela, Lagunju, Ike Oluwa, Marete, Irene, Zawolo, Jethro, Mwansa, Jonathan Kaunda, Chava, Joseph Tawanda, Baysah, Maima Kawah, Mudany, Mildred Anyango, Ngum, Nancy Biyeah Yang, Bell, Nellie V. T., Bayani, One, Samia, Pauline, Nduati, Ruth, Miti, Sam, Grodman, Schyler Zane, Mosalakatane, Thembisile Dintle, Abebe, Workeabeba, Coovadia, Ashraf   +32 more
openaire   +2 more sources

Exotic tropical fruits. The Courier No. 92, July/August 1985 [PDF]

, 1985

core