Results 261 to 270 of about 316,830 (312)

Regulating Tumor Metabolic Reprogramming with Biomimetic Co‐Delivery of Simvastatin and Kynureninase for Immunotherapy

Advanced Science, EarlyView.
After the intravenous injection of biomimetic and pH/ROS‐responsive PTSK@CRM, the nanoparticles can be accumulated in tumors and release Sim and KYNase to inhibit the tumor growth, regulate the metabolism of cholesterol and Kyn, and reverse the immunosuppressive tumor microenvironment.
Jiaxin Yin, Shengcai Yang, Zengguang Liu, Songchen Zhao, Siyu Sun, Ziling Liu, Quanshun Li   +6 more
wiley   +1 more source

Spine Trauma Resource Priorities in Sub-Saharan Africa: A Delphi Approach. [PDF]

Global Spine J
Wahle CF, Samuels C, Kakulamarri S, Adejuyigbe B, Tee T, Gomez Alvarado F, Morshed S, El Naga AN, Shearer DW, Gendelberg D, East Africa Spine Trauma Network, Africa Spine Trauma Delphi Study Group.   +11 more
europepmc   +1 more source

Tendon Organoids Enable Functional Tendon Rejuvenation Through ALKBH5‐Dependent RNA Demethylation

Advanced Science, EarlyView.
FT organoids reverse the aged phenotype of tendon cells, reinstating a fetal‐like state. This breakthrough establishes a potent cell source for tendon tissue engineering, effectively advancing regenerative medicine. ABSTRACT Adult tendon injuries pose a major clinical challenge due to limited self‐repair capacity, resulting in suboptimal regeneration ...
Tian Qin, Aini Pan, Zhuoning Miao, Yanyan Zhao, Xianan Mo, Heng Sun, Chunmei Fan, Junyu Guo, Bingbing Wu, Weiliang Shen, Qiangqiang Zheng, Jun Lu, Xi Jiang, Zi Yin, Xiao Chen   +14 more
wiley   +1 more source

Critical care in Gaza amidst military pressure: the struggle of healthcare workers in Gaza's Warzone. [PDF]

BMJ Glob Health
Barakat Y.
europepmc   +1 more source

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Sharps injuries in a dental specialty hospital: retrospective analysis of occupational risks, 2020-2024. [PDF]

BMC Oral Health
Zhang M, Chen Y, Zhang S, Fan X.
europepmc   +1 more source

Ultrasound-Guided Regional Anesthesia in a Resource-Limited Hospital: Prospective Pilot Study of a Hybrid Training Program.

JMIR Med Educ
Gamboa JE, Tamm-Daniels I, Flores R, Sarat Diaz NG, Villasenor MA, Gist MA, Hoie AB, Kurinec C, Simmons CG.   +8 more
europepmc   +1 more source

Sustainability in Aesthetic and Surgical Clinics: Impacts and Practical Interventions. [PDF]

Plast Reconstr Surg Glob Open
Goldie K, Viscomi B, Jackson MJ.
europepmc   +1 more source

Challenges in the medical oxygen ecosystem of Peru: A political economy analysis. [PDF]

PLOS Glob Public Health
Garcia PJ, Kitutu FE, Guzman JM, Najarro L, Ssengooba F, King C.   +5 more
europepmc   +1 more source