Results 41 to 50 of about 761,661 (289)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
How to look after and care for a slit lamp
Community Eye Health Journal, 2010 The slit lamp is an essential and often used diagnostic instrument in ophthalmology. It provides illumination and magnification for the examination of many structures of the anterior segment.
Cordero I
doaj
Optimized power converters for electrically augmented on-orbit propulsion systems
, 2002 Advances in satellite thruster technology have produced the requirement for high power electrical supplies to operate electrically augmented on-orbit propulsion systems.
Olyniec, Lee Michael
core +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Equipment repaired is equipment gained
Community Eye Health Journal, 2009 According to WHO, at any one time, around 50 per cent of medical equipment in low- and middle-income countries cannot be used because of lack of maintenance or spare parts. We have found that unwillingness or inability to repair equipment and put it back
V Srinivasan
doaj
Effects of a Combined Exercise Program Using an iPad for Older Adults [PDF]
Healthcare Informatics Research, 2016 ObjectivesThe purpose of this study was to examine the function, health status, and efficacy effects of a combined exercise program using an iPad among older women in Korea, a tech-savvy country.MethodsThe study employed a pretest and posttest ...
Juhee Lee +3 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Equipment maintenance and repair
Community Eye Health Journal, 2010 The repair and maintenance of ophthalmic equipment, including surgical instruments and diagnostic devices, can be compared to the maintenance of a motor vehicle, something many of us understand well.If you had a car, would you drive it until the fuel ...
Walia DS, Huria J, Cordero I.
doaj
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source