Results 51 to 60 of about 761,661 (289)

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

ARBITRAL RESOLUTIONS OF COMMERCIAL LITIGATIONS IN THE LIGHT OF UNCITRAL MODEL LAW

open access: yesPravo, 2013
The author points out the importance of a quality arbitral process, particularly in commercial disputes. The author analyzes the solution of UNCITRAL Model Law and order regarding the appointment of arbitrators, their characteristics, powers and ...
Miladin Pejak
doaj  

Development of an 360-degree virtual reality video-based immersive cycle training system for physical enhancement in older adults: a feasibility study

open access: yesBMC Geriatrics, 2021
Background Recently, there is an increased number of studies that use 360° virtual reality (VR) video for medical and rehabilitative purposes. However, the 360° VR video experience for older adults has not yet been investigated.
Namsu Lee, Wonjae Choi, Seungwon Lee
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Training for equipment maintenance and repair

open access: yesCommunity Eye Health Journal, 2010
In order to ensure the that equipment functions well, both equipment users and the equipment maintenance and repair team must be trained. Users must be trained in basic care and maintenance of equipment, and the equipment team must be trained to ...
Powdrill S, Cordero I,, Srinivasan V.
doaj  

Evaluation of Quality-Physical Requirements of Digital Mammography Facilities and Providing Improvement Strategies in Isfahan City, Iran

open access: yesمدیریت اطلاعات سلامت, 2019
Introduction: Mammography is the cornerstone of breast cancer screening and early detection. This study was conducted to investigate the status of digital mammography facilities in Isfahan City, Iran, in terms of equipment and physical-quality ...
Mitra Momenzade   +3 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Equipamento hospitalar no Brasil: presença, regionalização e tendências Hospital equipment in Brazil: presence, regionalization and tendency

open access: yesRevista de Saúde Pública, 1977
É apresentada uma análise do equipamento hospitalar existente no Brasil, especificamente quanto à sua distribuição geográfica e às tendências de seu desenvolvimento no período compreendido entre 1962 e 1971.
Ernesto Lima Gonçalves
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

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