Results 71 to 80 of about 17,986 (203)

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

[Supplies and equipment at the Forster Factory]

Photograph of supplies and equipment at the Forster Factory in Lanark ...

core   +1 more source

Unpacking supplies

, 2010
Athletic Medicine; Supplies being unpacked at the field house.
University Communications, Photo Services Department
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

[Various equipment supplies at the Forster Factory]

Photograph of equipment and supplies at the Forster Factory in Lanark ...

core   +1 more source

Quartermaster supplies, equipment and services during operations in extreme cold.

, 2008
This is a study of Quartermaster supplies, equipment, and services for use in operations where the temperatures may be as low as -20 degrees F.
Montgomery, John H.
core   +1 more source

Care of ophthalmic surgical instruments

Community Eye Health Journal, 2011
Good practice guidelines on handling and safety, maintenance and storage, transport, and security of surgical instruments.
Sue Stevens, Ingrid Mason
doaj  

Conditions for laryngeal mask airway placement in terms of oropharyngeal leak pressure: a comparison between blind insertion and laryngoscope-guided insertion

BMC Anesthesiology, 2019
Background Insertion under laryngoscopic guidance has been used to achieve ideal positioning of the laryngeal mask airway (LMA). However, to date, the efficacy of this technique has been evaluated only using fiberoptic evaluation, and the results have ...
Go Wun Kim, Jong Yeop Kim, Soo Jin Kim, Yeo Rae Moon, Eun Jeong Park, Sung Yong Park   +5 more
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Medical Supplies And Equipment Are Salvaged From Wrecked Ambulance.

, 1987
Photograph taken for a story in the Daily Oklahoman newspaper. Caption: "Medical supplies and equipment are salvaged from wrecked ambulance.
Vahlberg, Bob
core