Results 71 to 80 of about 87,963 (287)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Unpacking supplies

open access: yes, 2010
Athletic Medicine; Supplies being unpacked at the field house.
University Communications, Photo Services Department
core  

Purchasing equipment for an eye unit

open access: yesCommunity Eye Health Journal, 2010
If VISION 2020 is to meet its objective of eliminating avoidable blindness in ten years’ time, eye units have to ensure that they have the equipment they need so they can work quickly and effectively.
Cross C, Hoare P.
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Unpacking supplies in the fieldhouse

open access: yes, 2010
Athletic Medicine; Supplies being unpacked at the field house.
University Communications, Photo Services Department
core  

Availability of medical supplies and equipment in LLPHFs in Mbarara district, Uganda by location of the facilities.

open access: yes, 2021
Availability of medical supplies and equipment in LLPHFs in Mbarara district, Uganda by location of the facilities.
Grace Ndeezi (491009)   +8 more
core   +1 more source

Sharpening and tightening surgical scissors

open access: yesCommunity Eye Health Journal, 2011
How to test surgical scissors for sharpness, how to sharpen the scissors and how to tighten a loose joint.
Ismael Cordero
doaj  

EFFICACY OF MODIFIED MULTICOMPONENT SYSTEM “1C: ENTERPRISE” IMPLEMENTATION

open access: yesПедиатрическая фармакология, 2016
Background: Automated accounting and controlling system “1C: Enterprise” is widely used in Russia for optimizing the system of controlling materials and technical resources. Medical organizations modify them in line with their primary activity objectives.
A. A. Modestov, S. A. Dukoyan
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Home - About - Disclaimer - Privacy