Results 71 to 80 of about 744,000 (363)
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
ARBITRAL RESOLUTIONS OF COMMERCIAL LITIGATIONS IN THE LIGHT OF UNCITRAL MODEL LAW
Pravo, 2013 The author points out the importance of a quality arbitral process, particularly in commercial disputes. The author analyzes the solution of UNCITRAL Model Law and order regarding the appointment of arbitrators, their characteristics, powers and ...
Miladin Pejak
doaj
Impact of 3D printed medical equipment on the management of the Covid19 pandemic
International Journal of Health Planning and Management, 2020 Summary Very high mortality rates of coronavirus pandemic (COVID‐19) are observed around the world due to lack of medical equipment. The increased need for medical devices and personal protective equipment (PPE) has kept several healthcare professionals ...
S. Belhouideg
semanticscholar +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Improving quality of care through payment for performance: examining effects on the availability and stock-out of essential medical commodities in Tanzania. [PDF]
, 2016 OBJECTIVE: To evaluate the effects of payment for performance (P4P) on the availability and stock-out rate of reproductive, maternal, newborn and child health (RMNCH) medical commodities in Tanzania and assess the distributional effects.
Binyaruka, Peter, Borghi, Josephine
core +4 more sources
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Effectiveness of a compressive device in controlling hemorrhage following radial artery catheterization [PDF]
Clinical and Experimental Emergency Medicine, 2015 Objective The purpose of this study was to evaluate the effectiveness of a compressive device in controlling hemorrhage following radial artery catheterization.
Kiho Yun +3 more
doaj +1 more source
Perception of neonatology staff regarding the availability of equipment and supplies for the care of patients in need of nCPAP [PDF]
, 2022 Lorenzo Osorno-Covarrubias +5 more
openalex +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Training for equipment maintenance and repair
Community Eye Health Journal, 2010 In order to ensure the that equipment functions well, both equipment users and the equipment maintenance and repair team must be trained. Users must be trained in basic care and maintenance of equipment, and the equipment team must be trained to ...
Powdrill S, Cordero I,, Srinivasan V.
doaj