Results 71 to 80 of about 2,764,284 (341)

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

open access: yesMolecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane   +16 more
wiley   +1 more source

Research of equipment for pulsed heating supply

open access: yesIOP Conference Series: Materials Science and Engineering, 2020
Abstract Proposed scheme of individual heating unit (IHU) contains a mixing device based on energy-efficient two-flow membrane pump operating in pulse mode at available head of the heating network. The problem was solved of finding the optimal regimes of membrane pump work, which provided qualitative and economical efficacy of heating ...
E G Ezhov   +4 more
openaire   +2 more sources

Equipment maintenance and repair

open access: yesCommunity Eye Health Journal, 2010
The repair and maintenance of ophthalmic equipment, including surgical instruments and diagnostic devices, can be compared to the maintenance of a motor vehicle, something many of us understand well.If you had a car, would you drive it until the fuel ...
Walia DS, Huria J, Cordero I.
doaj  

Supplying bells and whistles in symmetric monoidal categories [PDF]

open access: yesarXiv, 2019
It is common to encounter symmetric monoidal categories $\mathcal{C}$ for which every object is equipped with an algebraic structure, in a way that is compatible with the monoidal product and unit in $\mathcal{C}$. We define this formally and say that $\mathcal{C}$ supplies the algebraic structure.
arxiv  

Strategies for Rational Use of Personal Protective Equipment (PPE) Among Healthcare Providers During the COVID-19 Crisis

open access: yesCureus, 2020
As the coronavirus 2019 (COVID-19) began spreading globally with no clear treatment in sight, prevention became a major part of controlling the disease and its effects. COVID-19 spreads from the aerosols of an infected individual whether they are showing
S. Mahmood   +4 more
semanticscholar   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

open access: yesMolecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren   +4 more
wiley   +1 more source

ARBITRAL RESOLUTIONS OF COMMERCIAL LITIGATIONS IN THE LIGHT OF UNCITRAL MODEL LAW

open access: yesPravo, 2013
The author points out the importance of a quality arbitral process, particularly in commercial disputes. The author analyzes the solution of UNCITRAL Model Law and order regarding the appointment of arbitrators, their characteristics, powers and ...
Miladin Pejak
doaj  

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Effectiveness of a compressive device in controlling hemorrhage following radial artery catheterization [PDF]

open access: yesClinical and Experimental Emergency Medicine, 2015
Objective The purpose of this study was to evaluate the effectiveness of a compressive device in controlling hemorrhage following radial artery catheterization.
Kiho Yun   +3 more
doaj   +1 more source

Optimization Models for Integrated Biorefinery Operations [PDF]

open access: yesarXiv, 2021
Variations of physical and chemical characteristics of biomass lead to an uneven flow of biomass in a biorefinery, which reduces equipment utilization and increases operational costs. Uncertainty of biomass supply and high processing costs increase the risk of investing in the US's cellulosic biofuel industry.
arxiv  

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