Results 41 to 50 of about 526,377 (298)
Chengshi guidao jiaotong yanjiu[Objective] In order to reduce the purchase cost and operation and maintenance cost of urban rail transit vehicles as much as possible, balanced maintenance system is adopted in some cities in China.
Tao HUANG, Zhengyuan ZHANG, Shixi SHI
doaj +1 more source
Development of a Safe Syringe Disposal System Moving towards Automated Syringe Data Collection [PDF]
Healthcare Informatics Research, 2019 ObjectivesAn automatic needle destroyer (ANDY) was developed to prevent needlestick injuries, and usability tests were conducted in several hospitals.
Youhwa Kim +3 more
doaj +1 more source
Molecular Oncology, EarlyView.In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim +11 more
wiley +1 more source
Applied SciencesHand fatigue commonly occurs in repetitive tasks, such as cutting with scissors, leading to discomfort, reduced productivity, and musculoskeletal disorders.
Kohei Koizumi +3 more
doaj +1 more source
Chimeric diphtheria toxin–CCL8 cytotoxic peptide for breast cancer management
Molecular Oncology, EarlyView.DTCCL8 is a recombinant fusion toxin that targets cancer cells expressing chemokine receptors. By combining diphtheria toxin with CCL8, DTCCL8 binds to multiple receptors on tumor cells and induces selective cytotoxicity. This strategy enables receptor‐mediated targeting of cancer and may support the development of chemokine‐guided therapeutics ...
Bernardo Chavez +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima +6 more
wiley +1 more source
Molecular Oncology, EarlyView.Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi +12 more
wiley +1 more source
3D printing of continuous cotton thread reinforced poly (lactic acid)
Scientific ReportsThis paper purposed to prepare poly (lactic acid)/continuous cotton thread (PLA /CCT) filaments by using prepreg method, and investigated the properties of PLA/CCT filament and their 3D printed composites.
Xiaohui Song +7 more
doaj +1 more source
VisionThis study compared the refraction measurements of the ClickCheck™ device (CCD), Topcon KR-8000, and subjective clinical refractometry (SCR) in Brazilian public school students with limited access to eye care. Eighty-seven eyes of healthy students aged 7
Francisco Carlos de Castro Neto +5 more
doaj +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source