Results 51 to 60 of about 573,638 (245)
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Chengshi guidao jiaotong yanjiu[Objective] In order to reduce the purchase cost and operation and maintenance cost of urban rail transit vehicles as much as possible, balanced maintenance system is adopted in some cities in China.
Tao HUANG, Zhengyuan ZHANG, Shixi SHI
doaj +1 more source
Micromachines, 2023 Plastic packaging has shown its advantages over ceramic packaging and metal packaging in lightweight, thin, and high-density electronic devices. In this paper, the reliability and moisture diffusion of Sop-8 (Small Out-Line Package-8) plastic packaging ...
Wenchao Tian +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
A Low-Energy Consumption Planning Method for Multi-Locomotion Wheel-Legged Mobile Robots
MachinesMobile robots can replace humans to fulfill tasks in dangerous environments, which has been a research focus in recent years. This paper proposes a wheel-legged mobile robot with multi-locomotion and a low-energy consumption planning method.
Jinfu Li +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
3D printing of continuous cotton thread reinforced poly (lactic acid)
Scientific ReportsThis paper purposed to prepare poly (lactic acid)/continuous cotton thread (PLA /CCT) filaments by using prepreg method, and investigated the properties of PLA/CCT filament and their 3D printed composites.
Xiaohui Song +7 more
doaj +1 more source
International Journal of Antennas and Propagation, 2018 Active electronically scanned array antenna (AESA antenna) is capable of controlling the radiation pattern by controlling the feeding phase of the radiating elements. It has good performance and plays an important role in radar systems.
Dan Han +6 more
doaj +1 more source