The Twenty Year Effect - Avoiding Back To The Future Scenarios In Failure Analysis [PDF]
, 2004 The Materials Investigation Group at Bluescope Steel's Port Kembla Steelworks has carried out diagnosis of failure mechanisms for 40 years, with problems emerging with new equipment, and regrettably, from time to time, the same lessons having to be ...
Christian, Kerrie Anne
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
THE BENEFITS OF FMEA IN IMPROVING THE INDUSTRIAL PROCESS OF A CABIN AIR CARRIER [PDF]
Proceedings on Engineering SciencesThis paper aims to present improvement actions to reduce the failure risk of a new vehicle cabin air transporter developed in an automotive plant in the Sul Fluminense region by applying the Failure Modes and Effect Analysis (FMEA) tool.
José Salvador da Motta Reis +5 more
doaj +1 more source
Practical extensions to the level of repair analysis [PDF]
, 2010 The level of repair analysis (lora) gives answers to three questions that are posed when deciding on how to maintain capital goods: 1) which components to repair upon failure and which to discard, 2) at which locations in the repair network to perform ...
Basten, R.J.I. +2 more
core +3 more sources
Current Distribution Based Power Module Screening by New Normal/Abnormal Classification Method with Image Processing [PDF]
, 2017 We developed a screening equipment for ceramic substrate level power module of IGBT. The equipment realizes a new screening test with current distribution.
Kim Hyoungseop +4 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
A framework for effective management of condition based maintenance programs in the context of industrial development of E-Maintenance strategies [PDF]
, 2016 CBM (Condition Based Maintenance) solutions are increasingly present in industrial systems due to two main circumstances: rapid evolution, without precedents, in the capture and analysis of data and significant cost reduction of supporting ...
Crespo Márquez, Adolfo +3 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Reliability analysis of distribution network [PDF]
, 2014 The knowledge of the reliability of distribution networks and systems is important consideration in the system planning and operations for development and improvements of power distribution systems. To achieve the target as minimum interruptions as
Anthony, Roystone
core
Criticality Analysis for Maintenance Purposes: A Study for Complex In‐service Engineering Assets [PDF]
, 2015 The purpose of this paper is to establish a basis for a criticality analysis, considered here as a prerequisite, a first required step to review the current maintenance programs, of complex in‐service engineering assets. Review is understood as a reality
Crespo Márquez, Adolfo +3 more
core +1 more source