Results 41 to 50 of about 1,634,230 (306)
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Learning chemistry is a learning process that simultaneously develops the cognitive, affective, and psychomotor aspects. Developing affective and psychomotor aspects, however, need learning support conducted in the laboratory in terms of practice and or ...
Ferli Septi Irwansyah +2 more
doaj +1 more source
Selection of Material Handling Equipment using the AHP and MOORA
Choosing the best Material Handling Equipment (MHE) is an aspect that needs to be considered in the industrial sector because the amount of capital involved in the procurement process is very large.
Sule I Satoglu, İbrahim Türkekul
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Selection of equipment for oil tank repair in northern conditions
Introduction. The oil industry is a key component of the economy of the Russian Federation. A large number of tanks are used to store oil, each of which needs timely repair.
V. N. Kuznetsova, I. S. Kuznetsov
doaj +1 more source
Guidelines for the use of cell lines in biomedical research [PDF]
Cell-line misidentification and contamination with microorganisms, such as mycoplasma, together with instability, both genetic and phenotypic, are among the problems that continue to affect cell culture.
Capes-Davis, A. +11 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Selection strategy of substation distribution unit based on management collaboration theory
Background: As the comprehensive development demands of power grid companies for substations continue to increase, traditional substation distribution equipment selection strategies, which only consider the life cycle cost theory, are no longer ...
Wenjie Xue +6 more
doaj +1 more source
Site selection of equipment and military equipment based on natural factors Case Study: Oman Sea Shores [PDF]
The coastal are geographically diverse from important areas for attracting populations and economic activities, especially military ones. Understanding the natural environment's behavior on the coast can help plan and deploy military activities ...
mohamda poodineh +3 more
doaj

