Results 41 to 50 of about 1,631,703 (286)

Expert system for tool wear monitoring in blanking [PDF]

open access: yes, 1992
A description is given of a simple yet powerful expert system created using the CRYSTAL shell which is able to monitor the potential and functional failures of the tool and the monitoring equipment.
Au, YHJ, Mardapittas, AS
core  

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Selection of Material Handling Equipment using the AHP and MOORA

open access: yesJurnal Teknik Industri, 2021
Choosing the best Material Handling Equipment (MHE) is an aspect that needs to be considered in the industrial sector because the amount of capital involved in the procurement process is very large.
Sule I Satoglu, İbrahim Türkekul
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

The Analysis of Determinant Factors in Selecting Laboratory Equipment in Chemistry Education Experiment

open access: yesChemical Engineering Transactions, 2018
Learning chemistry is a learning process that simultaneously develops the cognitive, affective, and psychomotor aspects. Developing affective and psychomotor aspects, however, need learning support conducted in the laboratory in terms of practice and or ...
Ferli Septi Irwansyah   +2 more
doaj   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

Selection of equipment for oil tank repair in northern conditions

open access: yesВестник СибАДИ, 2023
Introduction. The oil industry is a key component of the economy of the Russian Federation. A large number of tanks are used to store oil, each of which needs timely repair.
V. N. Kuznetsova, I. S. Kuznetsov
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Selection strategy of substation distribution unit based on management collaboration theory

open access: yesHeliyon
Background: As the comprehensive development demands of power grid companies for substations continue to increase, traditional substation distribution equipment selection strategies, which only consider the life cycle cost theory, are no longer ...
Wenjie Xue   +6 more
doaj   +1 more source

Site selection of equipment and military equipment based on natural factors Case Study: Oman Sea Shores [PDF]

open access: yesتحقیقات کاربردی علوم جغرافیایی, 2021
The coastal are geographically diverse from important areas for attracting populations and economic activities, especially military ones. Understanding the natural environment's behavior on the coast can help plan and deploy military activities ...
mohamda poodineh   +3 more
doaj  

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