Results 51 to 60 of about 1,644,647 (303)
Site selection of equipment and military equipment based on natural factors Case Study: Oman Sea Shores [PDF]
The coastal are geographically diverse from important areas for attracting populations and economic activities, especially military ones. Understanding the natural environment's behavior on the coast can help plan and deploy military activities ...
mohamda poodineh +3 more
doaj
A literature review on MHE selection problem: levels, contexts, and approaches [PDF]
This paper presents a review on selection problem of material handling equipment (MHE) and general equipment used in industry area. The issue on MHE is widely paid attention since MHE has contribution on material, good and product accomplishment.
Masudin, Ilyas +2 more
core +2 more sources
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Location of the target pitch within a vibrato wave
The current study investigated the relationship between the vibrato wave and the target pitch while eliminating some of the methodological problems that have plagued such research in the past.
Clark, David Frank
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
SYSTEMS ANALYSIS APPROACH TO SELECTION OF FARM EQUIPMENT [PDF]
Farm Management,
Barrick, Wendell C., Osborn, James E.
core +1 more source

