Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
Gravitational Biology Facility on Space Station: Meeting the needs of space biology [PDF]
The Gravitational Biology Facility (GBF) is a set of generic laboratory equipment needed to conduct research on Space Station Freedom (SSF), focusing on Space Biology Program science (Cell and Developmental Biology and Plant Biology).
Allen, Katherine, Wade, Charles
core +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Research of Oxidation Kinetics Testing Equipment for Coal Spontaneous Combustion Tendency
Gong-kuang zidonghua, 2012 The paper proposed a design scheme of oxidation kinetics testing equipment for coal spontaneous combustion tendency on the basis of oxidation kinetics testing method of coal spontaneous combustion tendency, and introduced working principle of the ...
XIAO Yang +3 more
doaj
Reliability analysis of wireless communication equipment based on model selection [PDF]
Zhihui kongzhi yu fangzhenThe research of equipment failure distribution is the basis of reliability engineering. In view of the complex structure and failure mechanism of wireless communication equipment, numerous failure distribution types, difficulty in selecting and ...
SUN Jin, HU Jicheng, JIAO Yaqi, WANG Kun
doaj +1 more source
Analisa Produktivitas Penggunaan Alat Berat Gali�Muat (Excavator) dan Alat Angkut (Dump truck) Terhadap Efisiensi Biaya Dan Waktu Pada Pekerjaan Spillway STA 1+25 S/D 6+50 Proyek Bendungan Bagong Tahap II Kabupaten Trenggalek [PDF]
Dam construction is an infrastructure project that has a central role in meeting water, energy and flood control needs in an area. In this context, heavy equipment such as Excavators and Dump Trucks are the backbone in supporting the smooth running
Farabi, Muhammad Farrel
core
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Multicriteria decision analysis: a multifaceted approach to medical equipment management
Technological and Economic Development of Economy, 2014 Selecting medical equipment is a complex multidisciplinary task requiring mathematical tools, considering associated uncertainties. This paper offers an in-depth study of multiple-criteria decision analysis (MCDA) methods to identify the most appropriate
Ilya Ivlev +2 more
doaj +1 more source
Design study of general aviation collision avoidance system [PDF]
The selection and design of a time/frequency collision avoidance system for use in general aviation aircraft is discussed. The modifications to airline transport collision avoidance equipment which were made to produce the simpler general aviation system
Bates, M. R., Moore, L. D., Scott, W. V.
core +1 more source
Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi +19 more
wiley +1 more source