Results 31 to 40 of about 167,018 (261)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Kesedaran terhadap amalan pemakanan seimbang dalam kalangan pelajar Politeknik Merlimau, Melaka: satu tinjauan [PDF]
, 2013 Pemakanan yang baik mula mempengaruhi kesihatan tubuh badan sejak daripada kecil lagi. Pemakanan memainkan peranan penting dalam mengekalkan kesihatan dan mencegah penyakit.
Saleh, Noorsyarzielah
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
Vojnotehnički Glasnik, 2016 Long rangers: SLCMs still add reach and strategic impact, Piranha 5: militaries remain hooked on proven platform, Will we ever build more F-22?, Russia's Next Super Submarine Is Almost Ready for War, Joint effort, New BMP-1 upgrade ...
Dragan M. Vučković
doaj +2 more sources
Silicon carbide equipments for process intensification of silicon reactions. [PDF]
, 2009 Bluestar Silicones, one of the worldwide leaders in silicones chemistry, proposes a R&D project, aiming to design new equipment for the transposition of batch to continuous processes. The safety and environmental issues linked to this type of chemicals,
Elgue, Sébastien +5 more
core
Cost of energy and mutual shadows in a two-axis tracking PV system [PDF]
, 2012 The performance improvement obtained from the use of trackers in a PV system cannot be separated from the higher requirement of land due to the mutual shadows between generators.
Alonso-García +23 more
core +2 more sources
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Modern weapons and military equipments for issue 1-2020 / Современное вооружение и военное оборудование, к выпуску № 1-2020 / Savremeno naoružanje i vojna oprema za broj 1-2020 [PDF]
Vojnotehnički Glasnik, 2020 Turkey uses laser weapon technology to shoot down Chinese UAV Wing Loong II in Libya; Forget Stealth Fighters: Is This Russia's Deadliest Warplane of All?;Russia Keeps Losing Its T-90 Tanks in Syria for One Reason; France’s First “Barracuda” Attack ...
Dragan M. Vučković
doaj
Behavioral modeling of power line communication channels for automotive applications [PDF]
, 2012 The black-box modeling of a power line communication channel in a car is addressed in this paper. The proposed behavioral approach is based on the so-called multipath model representation, that describes the transmission of a signal on a possibly complex
F.G. Canavero, I.S. Stievano
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source