Results 61 to 70 of about 256,327 (314)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Towards validation of a rational number instrument: An application of Rasch measurement theory
Pythagoras, 2019 The rational number knowledge of student teachers, in particular the equivalence of fractions, decimals, and percentages, and their comparison and ordering, is the focus of this article.
Jeremiah Maseko +2 more
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Traduci-los refráns. Elementos de tradutoloxía [PDF]
Cadernos de Fraseoloxía Galega, 2010 Este texto alude ó nacemento da Tradutoloxía e amosa de xeito breve e conciso as etapas esenciais da súa traxectoria. Evoca algúns conceptos capitais que xeran debate entre os especialistas na materia, como o da equivalencia ou o da interpretación do ...
Michel Quitout
doaj
UVn-equivalence and n-equivalence
Topology and its Applications, 1992 The following problem is considered: Suppose \(X\) and \(Y\) are two compacta embedded in the Hilbert cube \(Q\) as \(Z\)-sets. Can the property ``\(X\) and \(Y\) are \(\text{UV}^ n\)-equivalent (or \(n\)-equivalent)'' be described in terms of their complements \(Q-X\) and \(Q-Y\)?
openaire +2 more sources
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Adult Equivalence Scales, Inequality and Poverty [PDF]
This paper examines the sensitivity of inequality and poverty measures to the adult equivalence scale and the unit of analysis. Comparisons are made using parametric equivalence scales, and income units include individuals, equivalent adults and ...
Catherine Sleeman, John Creedy
core
Studies in African Languages and Cultures, 2012 In general, the purpose of translation - searching for cultural and semantic equivalents - is to reproduce various kinds of texts - including religious, literary, scientific, and philosophical texts - in another language and thus making them available ...
Abdalla Uba Adamu
doaj