Results 71 to 80 of about 1,262,397 (358)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Uniformity, Universality, and Computability Theory

open access: yes, 2017
We prove a number of results motivated by global questions of uniformity in computability theory, and universality of countable Borel equivalence relations. Our main technical tool is a game for constructing functions on free products of countable groups.
Marks, Andrew S
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Structural insights into lacto‐N‐biose I recognition by a family 32 carbohydrate‐binding module from Bifidobacterium bifidum

open access: yesFEBS Letters, EarlyView.
Bifidobacterium bifidum establishes symbiosis with infants by metabolizing lacto‐N‐biose I (LNB) from human milk oligosaccharides (HMOs). The extracellular multidomain enzyme LnbB drives this process, releasing LNB via its catalytic glycoside hydrolase family 20 (GH20) lacto‐N‐biosidase domain.
Xinzhe Zhang   +5 more
wiley   +1 more source

Keeping sites in sight: Conversations with teachers about the design of toolkits peculiar to a continuous professional development initiative

open access: yesPythagoras, 2019
The aim of this article is to shift the notion of ‘sites’ as places of work peculiar to continuous professional development (CPD) to a theoretical level, independent of, yet intimately connected to, their physical meanings, for example universities and ...
Faaiz Gierdien   +2 more
doaj   +1 more source

Flows equivalences

open access: yesApplied General Topology, 2001
<p>Given a differential equation on an open set O of an n-manifold we can associate to it a pseudo-flow, that is, a flow whose trajectories may not be defined in the entire real line. In this paper we prove that this pseudo-flow is always equivalent to a flow with its trajectories defined in all R. This result extends a similar result of Vinograd
openaire   +6 more sources

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

open access: yesFEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Translation Strategies and Equivalence in Formal Document Translation: A Study of UNESCO Agreements

open access: yesJournal of Languages and Language Teaching
This research investigates translation strategies and equivalence in translating Indonesian cultural terms in UNESCO agreements into English. The study aims to explore how translation strategies are adapted to address challenges in formal document ...
Ahmad Syafran   +4 more
doaj   +1 more source

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