Results 81 to 90 of about 1,262,397 (358)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Towards validation of a rational number instrument: An application of Rasch measurement theory
Pythagoras, 2019 The rational number knowledge of student teachers, in particular the equivalence of fractions, decimals, and percentages, and their comparison and ordering, is the focus of this article.
Jeremiah Maseko +2 more
doaj +1 more source
Regarding ‘Leibniz Equivalence’ [PDF]
Foundations of Physics, 2020 AbstractLeibniz Equivalence is a principle of applied mathematics that is widely assumed in both general relativity textbooks and in the philosophical literature on Einstein’s hole argument. In this article, I clarify an ambiguity in the statement of this Leibniz Equivalence, and argue that the relevant expression of it for the hole argument is ...
openaire +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Studies in African Languages and Cultures, 2012 In general, the purpose of translation - searching for cultural and semantic equivalents - is to reproduce various kinds of texts - including religious, literary, scientific, and philosophical texts - in another language and thus making them available ...
Abdalla Uba Adamu
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Traduci-los refráns. Elementos de tradutoloxía [PDF]
Cadernos de Fraseoloxía Galega, 2010 Este texto alude ó nacemento da Tradutoloxía e amosa de xeito breve e conciso as etapas esenciais da súa traxectoria. Evoca algúns conceptos capitais que xeran debate entre os especialistas na materia, como o da equivalencia ou o da interpretación do ...
Michel Quitout
doaj
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Achegas a un dicionario de refráns galego-castelán, castelán-galego [PDF]
Cadernos de Fraseoloxía Galega, 2003 Monográfico. Este terceiro número de “Cadernos de Fraseoloxía Galega” é unha monografía da autoría de María do Rosario Soto Arias. Nela ofrécenos equivalencias castelás duns 4.400 refráns galegos e as equivalencias galegas duns 4.100 refráns casteláns ...
María Rosario Soto Arias
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