Results 71 to 80 of about 166,055,931 (301)

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Adult Equivalence Scales, Inequality and Poverty in New Zealand [PDF]

open access: yes
This paper examines the sensitivity of inequality and poverty measures to the choice of adult equivalence scales and the type of income unit examined.
Catherine Sleeman, John Creedy
core  

Using Alignment Optimization to Test the Measurement Invariance of Gender Role Attitudes in 59 Countries

open access: yesMethoden, Daten, Analysen, 2018
Several repeated cross-national surveys include measurements of attitudes toward gender roles to investigate individuals’ beliefs regarding the appropriateness of men and women’s roles in a particular context.
Vera Lomazzi
doaj   +1 more source

Complexity measures from geometric actions onVirasoro and Kac-Moody orbits

open access: yesJournal of High Energy Physics, 2020
We further advance the study of the notion of computational complexity for 2d CFTs based on a gate set built out of conformal symmetry transformations.
Johanna Erdmenger   +2 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

The Comparability of Measures in the Ageism Module of the Fourth Round of the European Social Survey, 2008-2009

open access: yesSurvey Research Methods, 2020
Age is an important dimension that is used by people to categorize others. Age-based discrimination is directed toward specific age groups (young and old).
Daniel Seddig   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Adult Equivalence Scales, Inequality and Poverty [PDF]

open access: yes
This paper examines the sensitivity of inequality and poverty measures to the adult equivalence scale and the unit of analysis. Comparisons are made using parametric equivalence scales, and income units include individuals, equivalent adults and ...
Catherine Sleeman, John Creedy
core  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Inequality Measures, Equivalence Scales and Adjustment for Household Size and Composition [PDF]

open access: yes
Total household income inequality can be very different from inequality measured at the income per-capita level but only in recent years has the pattern of this divergence been investigated. In this paper, results from Coulter et al.
Paolo Figini
core  

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