Results 211 to 220 of about 352,444 (305)

Phase III Study to Confirm Clinical Similarity of MB09, a Denosumab Biosimilar, and Prolia^® in Postmenopausal Women with Osteoporosis (SIMBA Study). [PDF]

Pharmaceutics
Supronik J, Giorgadze E, Blicharski T, Sánchez-Vidaurre S, Pérez-Díaz L, Paravisini A, Millán S.   +6 more
europepmc   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

Arthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie, Timothy Beukelman, Nicholas P. McCormick, Jeffrey R. Curtis   +3 more
wiley   +1 more source

Scalable and Privacy-Conscious End-to-End Processing of Large-Scale Clinical Data for Precision Medicine: Empirical Evaluation Study.

JMIR Med Inform
Lee J, Hwang S, Lee KH.
europepmc   +1 more source

Author Correction: Feasibility study of hydrogen-ammonia synergistic combustion in scramjets across broad Mach ranges. [PDF]

Nat Commun
Song X, Cai Z, Ji J, Chen Z, Wang T, Li F, Sun M.   +6 more
europepmc   +1 more source

Evaluating a Pragmatic Strength Alternative for Frailty Measurement and Assessing Its Predictive Capacity Against Established Frailty Instruments in Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Objective Frailty occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health outcomes. We compared the performance of four frailty instruments, including a pragmatic alternative measure using chair sit‐to‐stand (STS), and evaluated their abilities to predict poor health outcomes.
Kylie E. Riggles, Hannah F. Brubeck, Adrienne D. Tanus, Courtney N. Loecker, Punyasha Roul, Bryant R. England, Elizabeth R. Wahl, James S. Andrews, Namrata Singh, Joshua F. Baker, Patricia P. Katz, Dolores M. Shoback, Jose M. Garcia, Ariela R. Orkaby, Katherine D. Wysham   +14 more
wiley   +1 more source

Super-Resolution Deep Learning Reconstruction Improves Image Quality of Dynamic Myocardial Computed Tomography Perfusion Imaging. [PDF]

Tomography
Kobayashi Y, Tanabe Y, Morikawa T, Yoshida K, Ohara K, Hosokawa T, Kouchi T, Nakano S, Yamaguchi O, Kido T.   +9 more
europepmc   +1 more source

Immune Checkpoint Inhibitor–Related Myositis and Associated Triad Overlap Syndrome

Arthritis Care &Research, EarlyView.
Objective Immune checkpoint inhibitor (ICI) myositis is a rare but a highly morbid condition, particularly with the ICI myositis triad syndrome of myositis, myocarditis, and myasthenia gravis. We report the clinical characteristics of ICI myositis and all‐cause mortality in these patients.
Selene Rubino, Grant W. Cannon, Brian C. Sauer, Jorge Rojas, Gregory J. Stoddard, Gary A. Kunkel, Jessica A. Walsh, Bryant R. England, Joshua F. Baker, Tawnie J. Braaten   +9 more
wiley   +1 more source

Bayesian adaptive trial designs for evaluating low-risk programmatic changes for quality improvement in health services: a simulation study. [PDF]

BMC Med Res Methodol
Kim MJ, Prieto-Merino D, Nicholas J, Allen L, Bastawrous A, Macleod D.   +5 more
europepmc   +1 more source

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

Arthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello, Rui Xiao, Xuemei Zhang, Jahan Jazayeri, Irit R. Rasooly, Pamela F. Weiss   +5 more
wiley   +1 more source

Exploring the Theoretical Foundation with Rupture and Delayed Rupture Experiments. [PDF]

Macromolecules
Siavoshani AY, Wang MC, Liang C, Jaisingh A, Wang J, Wang C, Wang SQ.   +6 more
europepmc   +1 more source