Results 81 to 90 of about 4,496,022 (300)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

WAYS TO INCREASE ACCURACY AND RELIABILITY OF INDIVIDUAL DOSES ASSESSMENTS IN PERSONNEL WITHIN THERMOLUMINESCENCE TECHNIQUE

Радиационная гигиена, 2015
The paper analyses the main sources of measurement errors of individual doses in personnel performed within the thermoluminescence technique and gives recommendations to minimize these errors.
G. N. Kaydanovskiy, E. N. Pirogova
doaj  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

LEVELS OF CHILDREN EXPOSURE FROM NATURAL IONIZING SOURCES AT CHILD EDUCATIONAL INSTITUTIONS IN THE TERRITORY OF SOME RUSSIAN FEDERATION SUBJECT TERRITORIES

Радиационная гигиена, 2015
The article presents results of research done for evaluation of the average annual equivalent equilibrium volumetric activity of radon isotopes in the air of premises of child educational institutions located in the territory of a number of Russian ...
I. P. Stamat, T. A. Kormanovskaya, A. V. Svetovidov, I. A. Rakitin, G. A. Gorsky   +4 more
doaj  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

BASED ON NEURAL NETWORK RELIABILITY STUDY OF SHEARER’S CUTTING PART

Jixie qiangdu, 2018
Roller is an important task of the coal winning machine cutting coal institutions,its structure and motion parameters will directly affect the working efficiency and working reliability of coal winning machine.Based on virtual prototype technology coal ...
ZHAO LiJuan, FAN JiaYi
doaj  

Fire‐Sale Spillovers and Systemic Risk

Journal of Finance, 2015
We construct a new systemic risk measure that quantifies vulnerability to fire-sale spillovers using detailed regulatory balance sheet data for U.S. commercial banks and repo market data for broker-dealers.
Fernando Duarte, T. Eisenbach
semanticscholar   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Should Western science institutions and scientists boycott their Russian equivalents? [PDF]

BMJ, 2022
openaire   +2 more sources