Results 81 to 90 of about 156,071 (279)
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The treatment of thin wire and coaxial structures in lossless and lossy media in FDTD by the modification of assigned material parameters [PDF]
, 2006 It has been shown recently that the use of modified assigned material parameters (MAMPs) within the finite-difference time-domain (FDTD) method provides a systematic, readily extensible, accurate, and efficient approach to the electromagnetic analysis of
Paul, DL, Dumanli, S, Railton, CJ
core +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source
SYNTHESIS OF THE THERMALLY COUPLED DISTILLATION SEQUENCES
Тонкие химические технологии, 2017 Approaching a hypothetical thermodynamically reversible process is one of the main directions of energy saving in distillation. In practice, this is achieved by the use of systems with coupled thermal and material flows (STMP).
E. А. Anokhina, А. V. Timoshenko
doaj +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Determination of Fracture Properties of Concrete Using Size and Boundary Effect Models
Applied Sciences, 2019 Tensile strength and fracture toughness are two essential material parameters for the study of concrete fracture. The experimental procedures to measure these two fracture parameters might be complicated due to their dependence on the specimen size or ...
Xiaofeng Gao +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia +3 more
wiley +1 more source
An Applicability of Equivalent Cracking Energy Concept for Impact Response Analysis of RC Girders [PDF]
, 2007 application/pdfHere, in order to establish a modification method for material properties of concrete so as to rationally analyze using coarse mesh, an equivalent fracture energy concept for concrete elements is proposed and the applicability was ...
岸, 徳光 +10 more
core +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source