Results 101 to 110 of about 71,040 (286)

Design and performance comparison of double-series and triple-series flexure hinges

open access: yes工程科学学报, 2017
The flexible hinge is one of the most important components in lamina emergent mechanisms (LEMs), so the design of a new type of lamina emergent torsional (LET) joint can play a key role in its movement performance.
QIU Li-fang   +3 more
doaj   +1 more source

Packed Hydrogel Microfibers as Scaffolds Supporting Dynamic Cellular Behavior and Biomaterial Inks in 3D Printing

open access: yesAdvanced Healthcare Materials, EarlyView.
Packed hydrogel microfiber (PHM) materials consist of flexible and high aspect ratio hydrogel components that, as a bulk material, are simultaneously mechanically robust and dynamic. Cells cultured in or on PHM scaffolds can be influenced by topographical cues or interact with a dynamic environment that permits cell spreading and multicellular ...
M. Gregory Grewal   +7 more
wiley   +1 more source

Multidimensional Cellular Micro‐Compartments to Model Invasive Lobular Carcinoma Dormancy

open access: yesAdvanced Healthcare Materials, EarlyView.
Invasive lobular carcinoma (ILC) is an understudied subtype of breast cancer that is susceptible to late recurrences. In this study, micro‐compartmentalization techniques spanning multiple dimensions, including 2D, pseudo‐3D, and 3D, are integrated to uncover the mechanisms underlying ILC dormancy, revealing the central role of p27Kip1.
Xilal Y. Rima   +15 more
wiley   +1 more source

Design of the Equivalent Stiffness in the 3-PCR Vibration Reduction Platform based on Genetic Algorithm

open access: yes, 2018
By installing spring-dampers in the active joints,the multi-dimensional damping platform is set up based on the 3-PCR parallel mechanism. The kinematics equation of the 3-PCR parallel mechanism is derived and the workspace is analyzed.
Zhang Fuliang   +3 more
core   +1 more source

Soft Neural Interfaces for Circuit‐Level Analysis of Magnetogenetic Deep Brain Stimulation in Parkinson's Disease Models

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT Magnetogenetic deep brain stimulation (MG‐DBS) represents a wireless neuromodulation that has demonstrated long‐lasting behavioral benefits in Parkinson's disease models. However, the circuit‐level mechanisms underlying these therapeutic effects have remained uncharacterized due to limitations of conventional neural interfaces.
Jakyoung Lee   +10 more
wiley   +1 more source

Influence of Anti-yaw Damper Series Stiffnesson Running Stability of High-speed EMUs

open access: yes机车电传动, 2015
The Maxwell model, which was the simplified model of anti-yaw damper, was introduced. High-speed EMUs model wasestablished by using SIMPACK. Based on nonlinear and linear stability analysis, the influence of anti-yaw damper series stiffness withdifferent
HE Yuan, WANG Yong
doaj  

Dynamic equivalent design and realization of the pipeline of engine fuel pump accessory

open access: yesHangkong gongcheng jinzhan
The pipeline space configuration of fuel pump accessory is complex,and it is difficult to simulate directly in vibration environment test. In this paper,the system equivalent reduction expansion process(SEREP)is used for the dynamic equivalent design of ...
LIU Jijun, LI Kaixiang, HU Wenjia
doaj   +1 more source

Tuning the Testicular Microenvironment for Enhancing Human Sertoli Cells Maturation and Functionality In Vitro

open access: yesAdvanced Healthcare Materials, EarlyView.
An in vitro testicular model is developed by generating connective tissue equivalents from human dermal fibroblast‐derived microtissues and coupling them with human Sertoli cells or human Sertoli cell spheroids. This engineered microenvironment supports Sertoli cell maturation and functionality, providing a promising platform for studying human ...
Annachiara Scalzone   +4 more
wiley   +1 more source

Physicochemical Reinforcement Unlocks Sterilization‐Stable Anisotropic Hydrogels for Cell‐Compatible Mock Arteries

open access: yesAdvanced Healthcare Materials, EarlyView.
ABSTRACT In vitro arterial models offer ethical and robust alternatives for vascular research but require cytocompatible materials that replicate physiological mechanics. Poly(vinyl alcohol) (PVA) hydrogels produced by directional freezing and salting‐out (PVA DFSO) are anisotropic yet lack stability for cell culture. Herein, methacrylated PVA (PVA‐MA)
Javiera Sanhueza Ortega   +4 more
wiley   +1 more source

Crushing study for interlocked armor layers of unbonded flexible risers with a modified equivalent stiffness method

open access: yes, 2019
Interlocked armor layers of unbonded flexible risers may crush when risers are being launched. In order to predict the behavior of interlocked armor layers, they are usually simplified as rings with geometric and contact nonlinearity ignored in the open ...
Fangguang Wu   +4 more
core   +1 more source

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