Results 11 to 20 of about 52,768 (118)
FEBS Open Bio, Volume 13, Issue 9, Page 1587-1600, September 2023., 2023 This review focuses on the impact of glycosphingolipids (GSLs), clustered within specific membrane contact sites (MCSs), on their protein and lipid compositions and function. Alterations in GSL levels at MCSs due to their abnormal catabolism affect their structural characteristics and signaling properties, leading to neurodegeneration in the lysosomal ...
Jason Andrew Weesner +3 more
wiley +1 more source
N‐glycosylation mediated folding and quality control in serine proteases of the hepsin family
The FEBS Journal, Volume 290, Issue 16, Page 3963-3965, August 2023., 2023 In this issue, Sun et al. assayed hepsin maturation and secretory transport to uncover the topological constraints for the location of N‐glycosylation in the scavenger receptor cysteine‐rich domain of hepsin. This may help unravel how key sites of N‐glycosylation are required for protein folding and transport and have evolved to select the lectin ...
John J. M. Bergeron, David Y. Thomas
wiley +1 more source
A cross-sectional study of immunohistochemical evaluation of surface epithelial ovarian tumors
MGM Journal of Medical Sciences, 2022 Background: Ovarian cancer is one of the most common malignancies in female patients. In recent years, immunohistochemistry (IHC) has emerged as an important tool in the diagnosis of ovarian tumors.
Vikas Pandey +2 more
doaj +1 more source
Journal of Neuroendocrinology, Volume 35, Issue 5, May 2023., 2023 Abstract Estrogens play a key role in learning and memory via delayed genomic and early‐onset rapid mechanisms. Systemic treatment with 17β‐estradiol (E2) rapidly facilitates object recognition, social recognition and object placement short‐term memory in ovariectomized female mice within a timescale of only 40 min following administration.
Talya Kuun‐Hadden +4 more
wiley +1 more source
Bond Strength of Resin Composite to Laser Treated Dentin Using Different Adhesive Systems (An in vitro study) [PDF]
Al-Rafidain Dental Journal, 2015 Aims: To evaluate the effect of three different adhesive systems on shear bond strength of composite resin to Er,Cr:YSGG lased dentin. Materials and methods: Twenty one sound third molars were used.
Zena A. Ahmed, Makdad N. Chakmakchi
doaj +1 more source
ER-Phagy: A New Regulator of ER Homeostasis [PDF]
Frontiers in Cell and Developmental Biology, 2021 The endoplasmic reticulum (ER) is one of the most important cellular organelles and is essential for cell homeostasis. Upon external stimulation, ER stress induces the unfolded protein response (UPR) and ER-associated degradation (ERAD) to maintain ER homeostasis. However, persistent ER stress can lead to cell damage.
Ming Yang +10 more
openaire +3 more sources
Onlinization of a simulation course that includes minor emergency procedures
Acute Medicine &Surgery, Volume 10, Issue 1, January/December 2023., 2023 We attempted to present a simulation course online to learn about the initial treatment of minor emergencies, which was held on‐site until the COVID‐19 pandemic. We reviewed the subjects covered in the course and evaluated whether these were “decision‐making” or “technical skills” that had primarily been taught as simulation‐based training for each ...
Tomoyasu Matsubara +3 more
wiley +1 more source
New Phytologist, Volume 236, Issue 3, Page 833-838, November 2022., 2022 Summary The number of described contact sites between different subcellular compartments and structures in eukaryotic cells has increased dramatically in recent years and, as such, has substantially reinforced the well‐known premise that these kinds of connections are essential for overall cellular organization and the proper functioning of cellular ...
Patricia Scholz +3 more
wiley +1 more source
FGF7/FGFR2–JunB signalling counteracts the effect of progesterone in luminal breast cancer
Molecular Oncology, Volume 16, Issue 15, Page 2823-2842, August 2022., 2022 Oestrogen receptor α (ER) and progesterone receptor (PR), in the presence of steroid hormones, form a direct complex which regulates expression of a gene set associated with a good prognosis in luminal breast cancer (BCa). Here, we suggest that FGF7/FGFR2‐triggered signalling, in the premenopausal patients, engages JunB to the transcriptionally active ...
Kamil Mieczkowski +11 more
wiley +1 more source
Acute Medicine &Surgery, Volume 8, Issue 1, January/December 2021., 2021 Aim Gunshot wounds (GSW) to the penis represent a rare type of traumatic injury in the civilian United States population. Although small, single‐center studies have reported results of care for these types of injured patients, no national analyses have examined this group. Methods A cohort of patients with GSW to the penis was identified using the 2017
Bryan G. Maxwell +3 more
wiley +1 more source