Results 71 to 80 of about 2,094,207 (229)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The monologue of the dove : reflections on life and death in an oral tradition of the Kwami People in northern Nigeria [PDF]
, 2006 The tale portrays the unhappy life of a dove. Constantly surrounded by enemies, hunted by human beings and animals, disappointed by friends and separated from her family, the dove despairs of her life.
Leger, Rudolf
core
Commutators and Anti-Commutators of Idempotents in Rings
, 2018 We show that a ring $\,R\,$ has two idempotents $\,e,e'\,$ with an invertible commutator $\,ee'-e'e\,$ if and only if $\,R \cong {\mathbb M}_2(S)\,$ for a ring $\,S\,$ in which $\,1\,$ is a sum of two units. In this case, the "anti-commutator" $\,ee'+e'e\
Khurana, Dinesh, Lam, T. Y.
core +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Strategies to Help Low-Wage Workers Advance: Implementation and Early Impacts of the Work Advancement and Support Center (WASC) Demonstration [PDF]
, 2009 Work Advancement and Support Center (WASC) is an innovative strategy to help low-wage workers increase their incomes by stabilizing employment, improving skills, increasing earnings, and easing access to work supports.
Betsy L. Tessler +2 more
core
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source
Developing the conditions for education for citizenship in higher education (CiCe network report) [PDF]
, 2008 The key questions surrounding education for citizenship in higher education are what is education for, what are universities for, and what values should education systems aim to develop in young people? These raise complex issues.
Essomba, Miquel Angel +4 more
core
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source