Results 81 to 90 of about 345,183 (190)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Ironia, tragedia, wspólnota: Richard Rorty w oczach barbarzyńcy
Er(r)go, 2009 Irony, Tragedy, Community: Richard Rorty in the Eyes of a Barbarian Abstract in English The essay is a perverse attempt at interpreting Richard Rorty from the perspective of a barbarian, that is, a person whom the author of “Contingency, Irony, and ...
Agata Bielik-Robson
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
W czerwieni i bieli - dialog transkulturowy i transkontynentalny
Er(r)go, 2008 Dagmara Drewniak's review of "TransCanadiania 2008/1", edited by Krzysztof Jarosz, Agnieszka Rzepa et al. (2008).
Dagmara Drewniak
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Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
Słuszność moralna a dzieło sztuki. Przypadek Knuta Hamsuna
Er(r)go, 2005 David Schauffler Moral Correctness and the Artwork. The Case of Knut Hamsun David Schauffler distinguishes five different levels on which one can consider the relation between art and politics: contextual, intentional, temporal, categorical, and finally ...
David Schauffler
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Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Między polityka a etyką: uwagi o dyskursach politycznej poprawności. Dwugłos krytyczny
Er(r)go, 2005 Djelal Kadir & Paweł Jędrzejko Between Self and State: on Discourses of Political Correctness. A Dialog The central issue of the present dialog is the ambivalence of the phenomenon of „political correctness”.
Djelal Kadir, Paweł Jędrzejko
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FEBS Open Bio, EarlyView.RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz +6 more
wiley +1 more source