Results 91 to 100 of about 1,717,234 (288)

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

open access: yesFEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia   +9 more
wiley   +1 more source

The Interim as developmental academic journal [PDF]

open access: yes, 2012
Published ArticleResearch has two important objectives: the contribution to scientific discourse and the identification of solutions for the challenges societies, government, business and industry face. Research should be in the public domain.
Kokt, D., Lategan, L., Dessels, R.
core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Evaluation of Satellite and Reanalysis Soil Moisture Products over Southwest China Using Ground-Based Measurements

open access: yesRemote Sensing, 2015
Long-term global satellite and reanalysis soil moisture products have been available for several years. In this study, in situ soil moisture measurements from 2008 to 2012 over Southwest China are used to evaluate the accuracy of four satellite-based ...
Jian Peng   +4 more
doaj   +1 more source

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

Tropopause sharpening by data assimilation

open access: yesGeophysical Research Letters, 2016
Data assimilation was recently suggested to smooth out the sharp gradients that characterize the tropopause inversion layer (TIL) in systems that did not assimilate TIL‐resolving observations.
R. Pilch Kedzierski, L. Neef, K. Matthes
doaj   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Evaluation of mechanisms of hot and cold days in climate models over Central Europe

open access: yesEnvironmental Research Letters, 2015
Changes in intensity, frequency, and location of temperature extreme events are a focus for many studies that often rely on simulations from climate models to assess changes in temperature extremes.
Oliver Krueger   +2 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Clearing of transient faults in MV networks [PDF]

open access: yes, 2015
Published ArticleThis paper contains research performed on the effectiveness of methods that aims to clear transient faults on MV networks without causing momentary supply loss to customers due to ARC operations, which is achieved by "instantaneous ...
Van Schalkwyk, W.J.D   +1 more
core  

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