Results 51 to 60 of about 36,611,446 (304)

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Serious invasions of privacy in the digital era: issues paper [PDF]

open access: yes, 2013
This Issues Paper was released on 8 October 2013, signalling the first stage of public consultation for the Serious Invasions of Privacy Inquiry. The paper provides background information and highlights issues identified by the Australian Law Reform ...

core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Blocking ASIP to Protect MC1R Signaling and Mitigate Melanoma Risk: An In Silico Study

open access: yesPharmaceuticals
Background: Melanin protects skin and hair from the effects of ultraviolet (UV) radiation damage, which contributes to all forms of skin cancer, including melanoma.
Farah Maarfi   +3 more
doaj   +1 more source

La publicación continua: un reto editorial

open access: yesRevista Colombiana de Ciencia Animal Recia, 2021
Los cambios que se están afrontando en esta nueva era digital, tales como el reemplazo del material impreso por el digital, el acceso restringido a al acceso abierto de la información, compras y ventas por internet, entre otros.
Luis C. Salgado-Arroyo   +3 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Three Eras of Digital Governance [PDF]

open access: yesSSRN Electronic Journal, 2019
Völkerrechtsblog
openaire   +2 more sources

Patienthood and participation in the digital era [PDF]

open access: yesDIGITAL HEALTH, 2019
The ‘digital era’ of informatics and knowledge integration has changed the roles and experiences of patients, research participants and health consumers. No longer figured (merely) as passive recipients of healthcare services or as beneficiaries of top-down biomedical information, individuals are increasingly seen as active contributors in healthcare ...
Sonja Erikainen   +3 more
openaire   +5 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Influencia del cromatismo en la estética fílmica: etalonaje y evolución visual a través de la tecnología digital

open access: yesArte, Individuo y Sociedad, 2019
El cine contemporáneo se enfrenta a una etapa crítica en su planteamiento ontológico. Rivalizado con la ficción televisiva, el universo digital y las nuevas manifestaciones multimedia, el cine ha desplegado innumerables resortes para remozar su estética ...
Lucía Tello
doaj   +1 more source

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