Results 121 to 130 of about 272,340 (307)
Global Polio Eradication progress 2003
The Global Polio Eradication Initiative achieved strong progress in 2003. By the end of 2003, only 6 countries in the world were still polio-endemic, the lowest number ever: Nigeria, India, Pakistan, Niger, Afghanistan and Egypt.WHO/Polio/04 ...
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Advanced Science, EarlyView.Helicobacter pylori infection induces sustained upregulation of the RNA‐binding protein IGF2BP1 in gastric epithelial cells, establishing a persistent epitranscriptomic program. IGF2BP1 stabilizes SLC7A11 mRNA in an m6A‐dependent manner to suppress ferroptosis and promote epithelial survival under oxidative stress. Pharmacological inhibition of IGF2BP1
Jing Ning +20 more
wiley +1 more source
Ghrelin Levels in Gastric Mucosa before and after Eradication of Helicobacter pylori
Gut and Liver, 2007 Background/Aims: The relationship between Helicobacter pylori infection and ghrelin is controversial. We compared ghrelin levels in gastric mucosa and plasma between H. pylori-positive and -negative subjects, and between before and after H.
doaj +1 more source
The Economic Effects of Malaria Eradication: Evidence from an Intervention in Uganda [PDF]
This study evaluates the economic consequences of a malaria eradication campaign in the southwestern Ugandan district of Kigezi. The project was a joint venture between the WHO and Uganda's Ministry of Health, designed to test for the first time the ...
Farshad Farzadfar +3 more
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Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer
Advanced Science, EarlyView.Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang +17 more
wiley +1 more source
Polio: abandoning eradication would result in rapid resurgence of an ancient scourge
BMJ Global Health, 2019 Roland Walter Sutter +1 more
doaj +1 more source
Gut and Liver, 2014 Background/AimsHelicobacter pylori eradication therapy has been used as a first-line treatment for H. pylori-positive gastric mucosa-associated lymphoid tissue (MALT) lymphoma. However, the management strategy for H. pylori-negative MALT lymphoma remains
doaj +1 more source
Global Polio Eradication progress 2000
The Global Polio Eradication Initiative, the largest public health initiative in history, is on track to certify the world polio-free in 2005. Polio cases have declined by 99% since the launch of the Initiative in 1988, from 350 000 to less than 3500 ...
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TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma
Advanced Science, EarlyView.TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin +9 more
wiley +1 more source