Results 101 to 110 of about 48,367 (290)

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

open access: yesAdvanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi   +16 more
wiley   +1 more source

Ustor: cloud storage system based on regenerating codes

open access: yesTongxin xuebao, 2014
To ensure reliability of user's data, multiple clouds are responsible for storing the data. For purpose of mini-mizing storage cost and repair bandwidth, a method of utilizing functional regenerating codes(FRC) to encode data to several blocks, which are
Qing LIU, Dan FENG, Bai LI
doaj   +2 more sources

Linear-time maximum likelihood decoding of surface codes over the quantum erasure channel

open access: yesPhysical Review Research, 2020
Surface codes are among the best candidates to ensure the fault tolerance of a quantum computer. In order to avoid the accumulation of errors during a computation, it is crucial to have at our disposal a fast decoding algorithm to quickly identify and ...
Nicolas Delfosse, Gilles Zémor
doaj   +1 more source

Density Evolution for Deterministic Generalized Product Codes with Higher-Order Modulation

open access: yes, 2016
Generalized product codes (GPCs) are extensions of product codes (PCs) where coded bits are protected by two component codes but not necessarily arranged in a rectangular array.
Amat, Alexandre Graell i   +3 more
core   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

open access: yesAdvanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

Continuous Symmetries and Approximate Quantum Error Correction

open access: yesPhysical Review X, 2020
Quantum error correction and symmetry arise in many areas of physics, including many-body systems, metrology in the presence of noise, fault-tolerant computation, and holographic quantum gravity.
Philippe Faist   +6 more
doaj   +1 more source

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

open access: yesAdvanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng   +16 more
wiley   +1 more source

Low-Complexity Codes for Random and Clustered High-Order Failures in Storage Arrays [PDF]

open access: yes, 2009
RC (Random/Clustered) codes are a new efficient array-code family for recovering from 4-erasures. RC codes correct most 4-erasures, and essentially all 4-erasures that are clustered.
Bruck, Jehoshua, Cassuto, Yuval
core   +1 more source

Duality between erasures and defects

open access: yes, 2016
We investigate the duality of the binary erasure channel (BEC) and the binary defect channel (BDC). This duality holds for channel capacities, capacity achieving schemes, minimum distances, and upper bounds on the probability of failure to retrieve the ...
Kim, Yongjune, Kumar, B. V. K. Vijaya
core   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

open access: yesAdvanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy