Results 91 to 100 of about 35,271 (280)

BGN/MDK Axis in the Melanoma Tumor Microenvironment Strengthens Tumor Malignancy by Modulating Cancer Cells and Cancer‐Associated Fibroblasts Crosstalk

Advanced Science, EarlyView.
This study reveals that m6A regulators cooperatively upregulate BGN in melanoma, promoting malignancy. Within the tumor microenvironment, CAFs show highest BGN expression. The BGN/MDK axis mediates cancer‐stroma crosstalk, driving normal fibroblast (NF) activation and enhancing the pro‐tumor effect of CAFs, highlighting a promising therapeutic target ...
Hao‐ze Shi, Ming‐yang Wu, Jin‐quan Liu, Cuicui Tian, Li Ma, Xue‐mei Zhou, Ze‐Hao Sun, Zhi‐yong Xu, Run‐dong Zhang, Shan‐yuan Ye, Li‐ming Huang, Yan Wang, Jing‐shu Xiong, Wen‐bo Bu, Xian‐feng Cheng, Jian‐fang Sun, Hao Chen   +16 more
wiley   +1 more source

On Minimizing the Maximum Broadcast Decoding Delay for Instantly Decodable Network Coding

, 2014
In this paper, we consider the problem of minimizing the maximum broadcast decoding delay experienced by all the receivers of generalized instantly decodable network coding (IDNC). Unlike the sum decoding delay, the maximum decoding delay as a definition
Al-Naffouri, Tareq Y., Alouini, Mohamed-Slim, Douik, Ahmed, Sorour, Sameh   +3 more
core   +1 more source

N4‐acetylcytidine in LncRNA Gm26917 Promotes Translation in Female Germline Stem Cells by Recruiting Ribosomal Protein mRNA via EEF1A1

Advanced Science, EarlyView.
This work establishes that ac4C modification on lncRNA Gm26917 governs its spatial interactions with Rpl10 mRNA, and RBP EEF1A1 mediates the interaction between Gm26917 and Rpl10. It elucidates a novel ac4C‐Gm26917‐EEF1A1‐Rpl10 axis in FGSC maintenance both in vitro and in vivo, and provides a potential molecular target for modulating germ cell ...
Xinyue Li, Xiaopeng Hu, Ji Wu
wiley   +1 more source

A Systematic Review on Cloud Storage Mechanisms Concerning e-Healthcare Systems

Sensors, 2020
As the expenses of medical care administrations rise and medical services experts are becoming rare, it is up to medical services organizations and institutes to consider the implementation of medical Health Information Technology (HIT) innovation ...
Adnan Tahir, Fei Chen, Habib Ullah Khan, Zhong Ming, Arshad Ahmad, Shah Nazir, Muhammad Shafiq   +6 more
doaj   +1 more source

Generating parity check equations for bounded-distance iterative erasure decoding

, 2006
A generic $(r,m)$-erasure correcting set is a collection of vectors in $\bF_2^r$ which can be used to generate, for each binary linear code of codimension $r$, a collection of parity check equations that enables iterative decoding of all correctable ...
Hollmann, Henk D. L., Tolhuizen, Ludo M. G. M.   +1 more
core   +2 more sources

ZSL Orchestrates Synaptonemal Complex Assembly as a Central Region Scaffold to Ensure Synapsis Fidelity and Crossover Control in Polyploid Meiosis

Advanced Science, EarlyView.
A central molecular adaptor, ZSL, is identified that links transverse filaments ZYP1 to central element SCEP1/2 to drive synaptonemal complex assembly in Brassica napus. Loss of ZSL abolishes synaptonemal complex formation, disrupts meiotic chromosome segregation, and markedly increases crossovers, providing mechanistic insight into meiotic fidelity ...
Miaowei Geng, Shaochen Jia, Fei Cao, Cuiping Liu, Heshuang Zhang, Gang Xu, Jixin Zhuang, Yashi Zhang, Can Liu, Yuhang Zhao, Zilin Guo, Xinjie Yuan, Jiaqing Yang, Lei Chu, Bowei Cai, Hu Zhao, Chao Yang   +16 more
wiley   +1 more source

Reducing the Bandwidth of Block Propagation in Bitcoin Network With Erasure Coding

IEEE Access, 2019
With the popularity of Bitcoin, there is a greater demand for the scalability of the Bitcoin blockchain, which is susceptible to the efficiency of block propagation. In the Bitcoin blockchain, efficient block propagation approach can reduce the computing
Ming Jin, Xiaojiao Chen, Sian-Jheng Lin
doaj   +1 more source

Intelligent cognitive spectrum collaboration: Convergence of spectrum sensing, spectrum access, and coding technology

Intelligent and Converged Networks, 2020
For a future scenario where everything is connected, cognitive technology can be used for spectrum sensing and access, and emerging coding technologies can be used to address the erasure of packets caused by dynamic spectrum access and realize cognitive ...
Peixiang Cai, Yu Zhang
doaj   +1 more source

Iterative Quantization Using Codes On Graphs

, 2003
We study codes on graphs combined with an iterative message passing algorithm for quantization. Specifically, we consider the binary erasure quantization (BEQ) problem which is the dual of the binary erasure channel (BEC) coding problem.
Martinian, Emin, Yedidia, Jonathan S.
core   +1 more source

A Circuit of Mechanically Regulated Transcription Factors Balances Regenerative and Fibrotic Memory of Mesenchymal Stromal Cells

Advanced Science, EarlyView.
Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi, Andrew E. Miller, Li Diao, Xinying Guo, Natalie Andonian, Elham Karimizadeh, Thomas H. Barker, Boris Hinz   +7 more
wiley   +1 more source