Results 171 to 180 of about 2,701,740 (294)

Precision Chemistry for Protein Lysine Modification

open access: yesChemistry – A European Journal, EarlyView.
Selective modification of lysine residues is challenging due to their similar intrinsic reactivity. Inspired by enzymatic recognition, ligand‐guided electrophiles enable site‐selective labeling and functionalization, while ligand‐guided catalyses achieve regioselective installation of bio‐relevant post‐translational modifications.
Mayu Onoda, Motomu Kanai
wiley   +1 more source

Purification, Fluorescent Labeling, and Detyrosination of Mammalian Cell Tubulin for Biochemical Assays

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules play essential roles in numerous cellular processes. All microtubules are built from the protein tubulin, yet individual microtubules can differ spatially and temporally due to their tubulin isotype composition and post‐translational modifications (PTMs).
Ezekiel C. Thomas   +5 more
wiley   +1 more source

Local realities, global discourses and decolonising the curriculum in a post‐92 UK context: Academic voices on enacting decolonial curriculum change

open access: yesThe Curriculum Journal, EarlyView.
Abstract This study explored how lecturers in a post‐92 UK university conceptualise and enact decolonial curriculum principles within their teaching and programme design. Drawing on semi‐structured interviews with academic staff across multiple disciplines, the research adopts a qualitative, phenomenologically informed approach to examine the interplay
Reece Sohdi
wiley   +1 more source

On the potential origin of the zygote-like cancer stem cell with a focus on fusion for cell rescue. [PDF]

open access: yesFront Cell Dev Biol
Cismaru CA   +4 more
europepmc   +1 more source

Bioinspired Crossmodal Tactile Sensory Nerve for High‐Accurate Object Recognition

open access: yesENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
An artificial crossmodal sensory neuron system (ACSNS) that combines a complementary memristor with high‐sensitivity pressure–temperature bimodal sensors, which integrate tactile perception, information storage, and neuromorphic computing. With the aid of machine learning, this ACSNS presents an improved accuracy of 96.67% in recognizing temperatures ...
Delu Chen   +8 more
wiley   +1 more source

Maternal obesity disrupts epigenetic reprogramming via peroxisomal-dependent phospholipid-methyl uncoupling during zygotic genome activation. [PDF]

open access: yesNat Commun
Zhang XG   +18 more
europepmc   +1 more source

The International Classification of Cognitive Disorders in Epilepsy (IC‐CoDE) Portal: An open source resource for neuropsychological research in epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective The International Classification of Cognitive Disorders in Epilepsy (IC‐CoDE) is a consensus‐based, empirically‐driven approach to standardize cognitive phenotyping in epilepsy research that has quickly garnered interest within the epilepsy community. However, manually generating IC‐CoDE phenotypes in group data is laborious and time‐
Robyn M. Busch   +11 more
wiley   +1 more source

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