The median preoptic nucleus is a key site for estradiol regulation of sleep-wake behaviors in females rats. [PDF]
Kruk K +7 more
europepmc +1 more source
In cardiovascular disease (CVD) patients, accelerated biological aging is independently associated with elevated mortality risk, which is mediated by neurodegenerative disease. Early‐onset CVD amplifies the mortality risk, whereas a healthy lifestyle confers partial protection.
Jinyue Li, Han Ma, Guohua Wang
wiley +1 more source
The miR-143/145 cluster in prostate cancer: molecular regulation, context-dependent functions, and medical implications. [PDF]
Stope MB, Erb HHH.
europepmc +1 more source
ERβ activation restores glucose and lipid homeostasis by remodeling the hepatic lipidome. Mechanistically, it promotes complete fatty acid oxidation and decreases Acetyl‐CoA levels, leading to reduced ketogenesis and lipotoxicity, as demonstrated through in vivo and in vitro approaches.
Debora Santos Rocha +9 more
wiley +1 more source
Sphingosine‐1‐Phosphate Receptor 1 Promotes Ovarian Cancer Tumorsphere Proliferation and Metastasis
In high‐grade serous ovarian cancer, malignant ascites frequently arise as ovarian cancer cells shed from the primary tumor and aggregate into tumorspheres, severely limiting treatment success. To date, little is known about the mechanisms governing tumorsphere endurance and metastasis within the ascites once formed.
Núria Gendrau‐Sanclemente +12 more
wiley +1 more source
A systematic review of psychometric scales that assess familial, lifestyle, and behavioural factors for children living with overweight or obesity, or at risk of developing obesity. [PDF]
Davis BÁ, O'Dwyer C, Carr A, Looney K.
europepmc +1 more source
Environmental toxicants may disrupt developmental pathways via strong molecular docking interactions with hub FGF proteins (FGF9 and FGF4) like dibenzo‐p‐dioxin (−7.2 kcal/mol) at the ASN146 residue of FGF9, driving congenital malformations as revealed by PPI networks and toxicity profiling.
Adarsh Kumar Shukla +3 more
wiley +1 more source
The impact of empathy with nature on tourists' responsible behavioral intentions in natural heritage tourism: the moderating roles of escapism and awe. [PDF]
Wang K, Huang S, Chen Z, Liu Y.
europepmc +1 more source
ABSTRACT Introduction The present study evaluates the psychometric properties and provides normative data for the Dutch Body Uneasiness Test. The instrument was administered to a clinical sample (N = 448) and a community‐based sample (N = 223). The Body Uneasiness Test was translated and back‐translated.
Lanaya M. van Uffelen +2 more
wiley +1 more source
Editorial Expression of Concern: Two novel human anti-ErbB2 immunoagents are active on trastuzumab-resistant tumours. [PDF]
Gelardi T +8 more
europepmc +1 more source

