Results 71 to 80 of about 576,050 (220)
Advanced Science, EarlyView.This review examines the potential of in vivo direct reprogramming in regenerative medicine for functional tissue restoration, highlighting the role of tissue‐resident cues in generating functionally mature reprogrammed cells from lineage‐related cells. It contains a discussion on mechanisms, reprogramming factors, delivery approaches, and applications
Rishabh Deo Singh +2 more
wiley +1 more source
Interaction of antibodies with ErbB receptor extracellular regions [PDF]
Experimental Cell Research, 2009 Antibodies to the extracellular region of the ErbB receptors have played key roles in the development of a mechanistic understanding of this family of receptor tyrosine kinases. An extensively studied class of such antibodies inhibits activation of ErbB receptors, and these antibodies have been the focus of intense development as anti-cancer agents. In
Karl R, Schmitz, Kathryn M, Ferguson
openaire +2 more sources
Molecular Oncology, 2023 Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest of cancers. Attempts to develop targeted therapies still need to be established. Some oncogenic mechanisms in PDAC carcinogenesis harness the EGFR/ERBB receptor family. To explore the effects
Kathrin Hedegger +7 more
doaj +1 more source
Brazilian Neurosurgery, 2023 Introduction According to the World Health Organization (WHO) classification, invasive breast carcinoma (IBC) of no special type (IBC-NST) is the second most common primary site of central nervous system metastases, affecting 15% to 30% of patients ...
Eduardo Cambruzzi +4 more
doaj +1 more source
Animal Research and One Health, EarlyView.ABSTRACT This study explored fasting‐induced physiological remodeling effects on meat quality in aged laying hens. Fasting for 15 days (F15) significantly reduced abdominal fat, intermuscular fat width, subcutaneous fat thickness, and liver index versus pre‐fasting (F0) (p < 0.05), which recovered post‐refeeding.
Xiaoran Zhang +8 more
wiley +1 more source
Frontiers in Cellular Neuroscience, 2018 Amyotrophic Lateral Sclerosis (ALS) is a devastating neurodegenerative disorder with no effective treatment currently available. Although the mechanisms of motoneuron (MN) death are still unclear, glutamate excitotoxicity and neuroinflammatory reaction ...
Guillem Mòdol-Caballero +7 more
doaj +1 more source
Animal Research and One Health, EarlyView.Supplementation with mannan oligosaccharides (MOS) enhances growth, disease resistance, antioxidant capacity, and gut microbiota diversity while suppressing inflammation, apoptosis, and strengthening intestinal barrier integrity in zebrafish challenged with LPS or DSS.
Zhiyuan Lu +4 more
wiley +1 more source
ErbB receptors in the biology and pathology of the aerodigestive tract [PDF]
Experimental Cell Research, 2009 The most common sites of malignancies in the aerodigestive tract include the lung, head and neck and the esophagus. Esophageal adenocarcinomas (EA), esophageal squamous cell carcinomas (ESCC), and squamous cell carcinomas of the head and neck (SCCHN) are the primary focus of this review.
Sarah, Morgan, Jennifer R, Grandis
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ErbB receptors profile in non-selected patients with endometrial cancer
, 2019 ErbB receptors are trans-membrane glycoproteins with tyrosine kinase activity. Especially in cancer, they are implicated in cell proliferation, transformation, angiogenesis, migration and invasion.
Adonakis Georgios +7 more
core +1 more source
The ErbB Receptors and Associated Key Signalling Proteins in Cancer
مجله كليه طب الكنديCancer is a disease of almost all multicellular organisms, in which communication between cells plays a crucial role in the life and development of that organism.
Ismail Al-Janabi
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