Results 161 to 170 of about 719,508 (214)

Human pancreatic cancer stem cells are sensitive to dual inhibition of IGF-IR and ErbB receptors. [PDF]

BMC Cancer, 2015
Urtasun N, Vidal-Pla A, Pérez-Torras S, Mazo A.   +3 more
europepmc   +1 more source

Recognition of ErbB Family Dimers by the EGF-like Domain of NRG1alpha and Beta: Implications for Ligand-Based CAR Therapy. [PDF]

Int J Mol Sci
Novikov A, Naumchik A, Banerji R, Greenshpan Y, Waidha K, Bhattacharya B, Elkabets M, Radinsky O, Porgador A.   +8 more
europepmc   +1 more source

ErbB family receptor dimerization dynamics and dysregulation via long-term single-molecule imaging. [PDF]

Cell
Ma K, Ma X, Shida JF, Niu Z, Lin YK, Mandal S, Dobbins A, Golomb L, Eck MJ, Greulich H, Meyerson M, Peng CS.   +11 more
europepmc   +1 more source

Neuregulin-1 facilitates myelin regeneration through microglia-mediated mechanisms in a mouse model of chronic demyelination. [PDF]

Nat Commun
Ziaee SM, Nemati S, Kataria H, Jakova E, Hosseini SM, Ghelich P, McLeod G, Tamayol A, Yong VW, Karimi-Abdolrezaee S.   +9 more
europepmc   +1 more source

Systemic Drug Effects in Vortioxetine-Induced Time-Series Datasets. [PDF]

Int J Mol Sci
Kim S.
europepmc   +1 more source

Epiregulin Binds to Epidermal Growth Factor Receptor and ErbB-4 and Induces Tryosine Phosphorylation of Epidermal Growth Factor Receptor, ErbB-2, ErbB-3 and ErbB-4 [PDF]

Oncogene, 1997
Epiregulin is a member of the epidermal growth factor (EGF) family, and has certain characteristics that are different from that of EGF, including mitogenic responses and binding to EGF receptor (EGFR). Epiregulin may also have another cell surface receptor and/or induces different receptor heterodimerizations for intracellular signaling.
T Komurasaki, Shigeo Morimoto, H Toyoda
exaly   +3 more sources

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The EGF/ErbB Receptor Family and Apoptosis

Growth Factors, 2002
The ErbB receptor family can activate a multitude of cell signaling pathways that involve many aspects of cellular function. The four members of the ErbB receptor family interact with diverse ligands and substrates, as well as with each other through cell surface heterodimerization.
Nita J Maihle
exaly   +3 more sources

Immune Responses to All ErbB Family Receptors Detectable in Serum of Cancer Patients

Oncogene, 1999
Employing NIH3T3 transfectants with individual human ErbB receptor coding sequences as recombinant antigen sources, we detected by immunoblot analysis specific immunoreactivity against all four ErbB receptors among 13 of 41 sera obtained from patients ...
Laura MASUELLI, Roberto Bei, Anna Moretti   +2 more
exaly   +2 more sources

Interaction of Antibodies With ErbB Receptor Extracellular Regions [PDF]

Experimental Cell Research, 2009
Antibodies to the extracellular region of the ErbB receptors have played key roles in the development of a mechanistic understanding of this family of receptor tyrosine kinases. An extensively studied class of such antibodies inhibits activation of ErbB receptors, and these antibodies have been the focus of intense development as anti-cancer agents. In
Kathryn M. Ferguson, Karl R Schmitz
exaly   +3 more sources