Results 111 to 120 of about 8,515 (264)

Epigenetic Markers of Cell Division and Ageing in Relation to Breast Cancer Survival

International Journal of Cancer, EarlyView.
ABSTRACT Breast cancer remains a major challenge to public health. Biomarkers may be useful to improve prediction of breast cancer survival. Several epigenetic markers of cell division and ageing based on DNA methylation have been proposed. In this study, we measured these epigenetic markers in breast tumours and assessed their prognostic value.
Luca Li, Elaheh Zarean, Danmeng Lily Li, Yiyue Zhu, Shuai Li, Enes Makalic, Catriona McLean, Graham G. Giles, Roger L. Milne, Melissa C. Southey, Pierre‐Antoine Dugué   +10 more
wiley   +1 more source

Air Pollution Quinones Impair Intestinal Barrier Integrity and Endoplasmic Reticulum in Differentiated Caco‐2 Cells

Journal of Applied Toxicology, EarlyView.
ABSTRACT Particulate matter (PM) is a major global health threat, linked to millions of deaths annually. Beyond inhalation, PM components reach the gastrointestinal tract through the mucociliary escalator or contaminated food and water. Among PM's organic fraction, redox‐active quinones such as 1,2‐naphthoquinone (NQ) and 9,10‐phenanthrenequinone (PQ ...
Franco Cervellati, Giulia Trinchera, Alice Casoni, Alessandra Pecorelli, Mascia Benedusi, Maria Chiara Pietrogrande, Giuseppe Valacchi   +6 more
wiley   +1 more source

Diagnostic Performance of Comprehensive Point‐of‐Care Ultrasound for Pediatric Tuberculosis in Spain: A Prospective Observational Study

Journal of Clinical Ultrasound, EarlyView.
In children with presumptive tuberculosis, comprehensive point‐of‐care (cPOCUS) identified key thoracic abnormalities with high specificity and excellent inter‐reader reliability. Although diagnostic sensitivity was modest and examinations often incomplete, cPOCUS shows promise as a complementary, radiation‐free imaging tool.
Isabelle Munyangaju, Antoni Noguera‐Julian, Aleix Soler‐Garcia, Antoni Soriano‐Arandes, José Miguel Escudero Fernández, Maria Espiau, Begoña Santiago Garcia, Alicia Hernanz‐Lobo, Ángel M. Lancharro Zapata, Enrique Ladera, Angela Manzanares, Daniel Blazquez, Elisa Aguirre Pascual, Isabelle Thierry‐Chef, Danilo Buonsenso, Xavier Serres‐Créixams, Quique Bassat, Elisa Lopez‐Varela   +17 more
wiley   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Examining stressful life experiences as risk factors for self‐injurious behaviors as a function of sexual minority status in adults

Journal of Traumatic Stress, EarlyView.
Abstract Self‐injurious behaviors (SIBs) represent a major public health concern in the United States. Although sexual minority individuals experience disproportionately high rates of SIBs, research identifying population‐specific risk factors remains limited. This study examined how stressful experiences common among sexual minority (SM) adults relate
Samantha M. Haas, Naomi Sadeh
wiley   +1 more source

Recent Advances in Photonic Bound States in the Continuum: From Fundamentals to Engineering and Implementation

Laser &Photonics Reviews, EarlyView.
This review summarizes recent progress in meta‐photonics with a focus on bound states in the continuum (BICs) as a powerful platform for light confinement and control. It covers fundamental concepts, design strategies across optical regimes, symmetry breaking for practical quasi‐BICs, tunable and AI‐assisted BIC devices, and emerging applications in ...
Hafiz Saad Khaliq, Hak‐Rin Kim
wiley   +1 more source

Octave‐Spanning, Deterministic Single Soliton Generation in 4H‐Silicon Carbide‐On‐Insulator Microring Resonators

Laser &Photonics Reviews, EarlyView.
The miniaturization of metrology and precision spectroscopy systems requires robust, turn‐key microcombs with broad bandwidth, low threshold, and high efficiency. Here, high‐Q, dispersion‐engineered microresonators in a high‐confinement nonlinear SiC platform, combined with waveguide‐enabled thermal management and laser cooling, enable deterministic ...
Yi Zheng, Liping Zhou, Chengli Wang, Yanjing Zhao, Ailun Yi, Kresten Yvind, Xin Ou, Minhao Pu   +7 more
wiley   +1 more source

Stimulated Forward Brillouin Scattering in Subwavelength Grating Silicon Membranes

Laser &Photonics Reviews, EarlyView.
This work proposes a novel strategy to achieve large Brillouin scattering with independent control of the optical and mechanical modes using subwavelength silicon membranes. We experimentally demonstrate remarkably high Brillouin gain, resulting in an on/off Stokes gain of 3 dB and anti‐Stokes loss of 4 dB in a 6 mm‐long waveguide with 35 mW of on‐chip
Paula Nuño Ruano, Jianhao Zhang, David González‐Andrade, Daniele Melati, Eric Cassan, Pavel Cheben, Laurent Vivien, Norberto Daniel Lanzillotti‐Kimura, Carlos Alonso‐Ramos   +8 more
wiley   +1 more source

Ultrahigh‐Order Harmonic Mode‐Locked Optoelectronic Oscillator

Laser &Photonics Reviews, EarlyView.
This article demonstrates a record‐breaking microwave frequency comb generator using an ultrahigh‐harmonic‐order mode‐locked optoelectronic oscillator. By integrating dual recirculating loops into a low‐coherence system, the researchers achieved a harmonic order of 956 with superior noise suppression.
Zhuoran Wang, Santiago Bernal, David V. Plant, Lawrence R. Chen   +3 more
wiley   +1 more source

Broadband Parametric Amplification in AlGaAs‐on‐Insulator Nanowaveguides

Laser &Photonics Reviews, EarlyView.
Harnessing the exceptional nonlinearity of AlGaAs‐on‐insulator nanowaveguides, four‐wave‐mixing parametric amplification achieves a record net on‐chip gain of 56 dB and a gain bandwidth exceeding 415 nm at telecom wavelengths. These results establish AlGaAsOI as a powerful platform for compact, high‐performance integrated nonlinear optical ...
Yanjing Zhao, Chanju Kim, Yi Zheng, Chaochao Ye, Yueguang Zhou, Kresten Yvind, Minhao Pu   +6 more
wiley   +1 more source