TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
AI Research Funding Portfolios and Extreme Growth
Frontiers in Research Metrics and Analytics, 2021 Our work analyzes the artificial intelligence and machine learning (AI/ML) research portfolios of six large research funding organizations from the United States [National Institutes of Health (NIH) and National Science Foundation (NSF)]; Europe ...
Ilya Rahkovsky +4 more
doaj +1 more source
A Different Perspective on the Solid Lubrication Performance of Black Phosphorous: Friend or Foe?
Advanced Engineering Materials, EarlyView.Researchers investigate black phosphorous (BP) as a standalone solid lubricant coating through ball‐on‐disc linear‐reciprocating sliding experiments in dry conditions. Testing on different metals shows BP doesn't universally reduce friction and wear. However, it achieves 33% friction reduction on rougher iron surfaces and 23% wear reduction on aluminum.
Matteo Vezzelli +5 more
wiley +1 more source
Innovation diplomacy caught between the two opposing logics of cooperation and competition: Case study on EU-China S&T cooperation in the field of solar PV. EL-CSID Working Paper Issue 2018/15 • April 2018 [PDF]
, 2018 The purpose of this study is to test this question on the basis of a highly interesting illustrative case. It concerns the domain of the solar photovoltaics (solar PV) and the competition between the EU and China in this field.
Gehrt, Daniel
core
3D Bioprinting of Thick Adipose Tissues with Integrated Vascular Hierarchies
Advanced Functional Materials, Volume 35, Issue 12, March 18, 2025.An advanced 3D bioprinting technique is used here to create thick adipose tissues with a central, vessel and extensive branching. The construct is made using alginate, gelatin and collagen‐based bioinks. Flow through the complex vessel network is demonstrated as well as its successful integration with a femoral artery following implantation in a rat ...
Idit Goldfracht +5 more
wiley +1 more source
An unusual cause of shortness of breath and fever [PDF]
, 2005 A case of a 57 year old man who presented with shortness of breath and fever is discussed . The patient was suffering from multiple lung abscesses.
Cachia, Mario J., Despott, Edward
core
Tunable Tactile Synapses Enabled by Erasable Doping in Iongel‐Gated Nanotube Network Transistors
Advanced Functional Materials, EarlyView.Artificial tactile synaptic sensors are realized by an iongel‐gated single‐walled carbon nanotube (SWCNT) transistor with reversible doping characteristics. The device senses and memorizes tactile stimuli and exhibits gate bias‐dependent excitatory or inhibitory synaptic behavior.
Yan Huang +5 more
wiley +1 more source
Building Evaluation Muscle: Practical Steps for Health Nonprofits at Any Stage [PDF]
, 2015 This paper bridges the academic literature and ordinary practice to show how nonprofit organizations, regardless of where they are on the spectrum of evaluation capacity, and regardless of their desire to conduct evaluation internally or use external ...
core
On Probability of Support Recovery for Orthogonal Matching Pursuit Using Mutual Coherence
, 2017 In this paper we present a new coherence-based performance guarantee for the Orthogonal Matching Pursuit (OMP) algorithm. A lower bound for the probability of correctly identifying the support of a sparse signal with additive white Gaussian noise is ...
Afshari, Ehsan +3 more
core +1 more source
Scientometrics: Untangling the topics [PDF]
, 2014 Measuring science is based on comparing articles to similar others. However, keyword-based groups of thematically similar articles are dominantly small. These small sizes keep the statistical errors of comparisons high.
Farkas, Illes J. +3 more
core +2 more sources