Results 61 to 70 of about 4,926,805 (180)
Doença de Erdheim-Chester: relato de caso
, 2021 A doença de Erdheim-Chester é uma rara histiocitose de células não-Langerhans, primeiramente descrita por Jakob Erdheim e William Chester em 1930 de etiologia desconhecida.
Giongo, Aline Alencar +3 more
core +1 more source
Outcome of treatment with trametinib in adults with histiocytic neoplasms in the United Kingdom
British Journal of Haematology, Volume 209, Issue 2, Page 747-754, August 2026.Trametinib (MEK inhibitor) shows efficacy in refractory and high‐risk adult histiocytic neoplasms. At a median follow‐up of 21.4 months, the clinical response rate was 81% (30/37) and the radiological response was 68% (25/37) (n = 37).
Rodothea Amerikanou +15 more
wiley +1 more source
La tamponnade, un mode révélateur de la maladie d’Erdheim-Chester
Journal de la Faculté de Médecine d'Oran, 2022 La maladie d’Erdheim-Chester est une maladie rare. C’est une histiocytose non langerhansienne qui affecte de nombreux organes avec des localisations osseuses, rétro péritonéales, pulmonaires, cardiovasculaires, neurologiques et orbitaires.
Dalila Ahnou +2 more
doaj
Clinical Pharmacology &Therapeutics, Volume 120, Issue 1, Page 274-285, July 2026.BRAF inhibitors and MEK inhibitors (MEKi) have reshaped the treatment of BRAFV600‐mutant malignancies; however, cutaneous adverse drug reactions (ADRs) remain a frequent and clinically impactful toxicity. Although clinical trials provide insight into their safety profiles, real‐world data on dermatologic ADRs are limited.
Natalia Sauer +3 more
wiley +1 more source
Erdheim-chester disease: A case report
, 2015 Objective: Rare disease Background: The diagnosis of Erdheim-Chester disease, a rare illness, is difficult and requires increased awareness. Case Report: We report the case of a 56-year-old woman who initially presented with a mesenteric panniculitis and
Klastersky, Jean, Alexiou, Jean
core +1 more source
Neurological manifestations of Erdheim–Chester Disease
Annals of Clinical and Translational Neurology, 2020 Objective To characterize the spectrum of neurologic involvement in Erdheim–Chester Disease (ECD), a treatable inflammatory neoplasm of histiocytes.
Louisa C. Boyd +11 more
doaj +1 more source
Orbital mass and hairy kidney as characteristics of Erdheim‐Chester disease
Clinical Case Reports, 2021 Erdheim‐Chester disease (ECD) is a rare non‐Langerhans cell histiocytosis, involving multiple organs. We report a case of ECD with typical features of an orbital mass and "hairy kidneys," whose recognition can lead to early diagnosis and treatment.
Koichiro Yamamoto +3 more
doaj +1 more source
Statistics in Medicine, Volume 45, Issue 15-17, July 2026.ABSTRACT Many molecular‐targeted oncology drugs have been successfully developed. The mechanism to target some specific molecules gives us the expectation that the molecular‐target drug is effective over multiple tumor types and histologies. Then, simultaneous evaluation of multiple subtypes is motivated, and the basket trials aim to realize it, in ...
Shunya Tanaka +2 more
wiley +1 more source
Cardiac MRI Imaging Features of Erdheim–Chester Disease: A Case Review [PDF]
Erdheim–Chester disease (ECD) is a disease of non-Langerhans cell histiocyte multisystemic proliferation. The pathogenesis is related to accumulation of histiocytes across the body, leading to multiple organ failure, and thus necessitating an early ...
Chris Schettino +7 more
core +1 more source
A case of Erdheim-Chester disease initially mistaken for retroperitoneal lymphoma
Radiology Case Reports, 2020 Erdheim-Chester disease (ECD) is an infrequent, autoimmune disorder that is not Langerhans histiocytosis and is characterized by bilateral sclerosis of the diametaphyseal medullary regions of the long bones and possible multiorgan involvement.
Sharifa K. Alduraibi, MD
doaj +1 more source