Results 21 to 30 of about 53,688 (287)

Effect of Pupil Size on Fixed-Luminance Flicker Full-Field Electroretinogram Magnitude

Clinical Ophthalmology, 2022
Azadeh Mobasserian,1,* Moosa Zaidi,1,* Sohail Halim,1,2 Jaclyn Joyce Hwang,1 Jonathan Regenold,1 Amir Akhavanrezayat,1 Irmak Karaca,1,3 Hassan Khojasteh Jafari,1 Negin Yavari,1 Wataru Matsumiya,1,4 Cigdem Yasar,1,5 Ngoc Tuong Trong Than,1 Gunay ...
Mobasserian A, Zaidi M, Halim S, Hwang JJ, Regenold J, Akhavanrezayat A, Karaca I, Khojasteh Jafari H, Yavari N, Matsumiya W, Yasar C, Than NTT, Uludag G, Do D, Ghoraba H, Nguyen QD   +15 more
doaj  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

The importance of histomorphological features and ERG expression in the diagnosis of malignancy in cases with atypical small acinar proliferation [PDF]

Journal of Pathology and Translational Medicine
Background Atypical small acinar proliferation (ASAP) cases typically require rebiopsy, which are invasive and associated with increased risk of complications.
Gizem Teoman, Ayten Livaoglu, Hatice Kucuk, Afşın Rahman Murtezaoglu   +3 more
doaj   +1 more source

FeDSNP‐Pa Nanoassemblies: A Triple‐Action Therapeutic Strategy Targeting Oxidative Stress, Inflammation, and Pyroptosis for Retinal Ganglion Cell Protection in Glaucoma

Advanced Functional Materials, EarlyView.
FeDSNP‐Pa, a metallized nanoparticle loaded with sodium pyruvate (Pa), exerts triple therapeutic effects by scavenging reactive oxygen species (ROS), suppressing inflammatory responses, and inhibiting pyroptosis signaling pathways. This multifunctional neuroprotective strategy protecting retinal ganglion cells (RGCs) from elevated intraocular pressure ...
Yukun Wu, Xue Li, Tong Wu, Dan Ji, Yugang Bai, Xuezhi Zhou   +5 more
wiley   +1 more source

Molecular pathways driven by ETO2-GLIS2 in aggressive pediatric leukemia

Molecular & Cellular Oncology, 2017
The ETO2-GLIS2 fusion oncoprotein is associated with poor prognosis pediatric acute megakaryoblastic leukemia. Recently, we observed that ETO2-GLIS2 controls enhancers activity at genes regulating haematopoietic progenitor self-renewal and ...
Cécile Thirant, Cécile Lopez, Sébastien Malinge, Thomas Mercher   +3 more
doaj   +1 more source

Tissue Expression of ETS-Related Gene in Gastric Carcinomas

Forbes Tıp Dergisi, 2020
INTRODUCTION: The ETS-related gene (ERG) encodes a member of the erythroblast transformation-specific (ETS) transcription factor family that has been implicated in both tumor invasion and neovascularization.
Sevil Sayhan, Gulden Diniz, Ismail Eren Birol, Dudu Solakoglu Kahraman, Bulent Calik   +4 more
doaj   +1 more source

Ophthalmic Bioengineering. Review

Oftalʹmologiâ, 2023
This article published the materials of the round table “Bioengineering in ophthalmology” (OphthalmicBioengineering), held on May 13, 2021 as part of the international conference Ural Symposium on Biomedical Engineering, Radioelectronics and Information ...
V. O. Ponomarev, A. E. Zhdanov, P. V. Luzhnov, I. D. Davydova, E. N. Iomdina, A. V. Lizunov, A. Yu. Dolganov, S. A. Ivliev, M. A. Znamenskaya, V. N. Kazajkin, V. I. Borisov, E. O. Filatova   +11 more
doaj   +1 more source

Wetting Interactions Between Porous Carbon Hosts and Liquid Sodium‐Potassium Alloys Toward Their Use in Negative Electrodes of Alkali‐Metal Batteries

Advanced Functional Materials, EarlyView.
Porous carbon host materials are investigated for their possible usage in liquid alkali‐metal negative electrodes. X‐ray computed tomography reveals pore‐filling behavior under various conditions: non‐wetting, forced wetting, and spontaneous wetting. The applicability of porous carbon in electrochemical cells is demonstrated at high areal capacities ...
Johannes Baller, André Hilger, Naiyu Qi, Chiara Morini, Andrea Cornelio, Arndt Remhof, Markus Osenberg, Ingo Manke, Julian Moosmann, Felix Beckmann, Gustav Graeber   +10 more
wiley   +1 more source

A Precisely Bromo‐Functionalized [9]Cycloparaphenylene as a Platform for Late‐Stage Multisite π‐Extension Toward Chiral Nanohoops

Angewandte Chemie, EarlyView.
Precisely synthesized hexabrominated [9]cycloparaphenylene (CPP), accessed by a gold‐mediated method, enables efficient multisite post‐functionalization through cross‐coupling reactions. Late‐stage π‐extension on the CPP framework successfully affords armchair‐type chiral nanohoops exhibiting strong circularly polarized luminescence (|glum| = 0.100 ...
Naoya Kinoshita, Nanami Kotani, Masaya Sugiura, Kotaro Matsumura, Daisuke Sakamaki, Daiki Tauchi, Masashi Hasegawa, Hidetoshi Kawai, Yoshitaka Tsuchido   +8 more
wiley   +2 more sources

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source