Results 171 to 180 of about 5,284 (235)

Global and Regional Vigilance: Are There Two Types of Local Sleep?

open access: yesBrain and Behavior, Volume 16, Issue 4, April 2026.
The term local sleep as it is used in the literature is confusing and probably consists of two types of brain states. The first one originates from increased activity in certain cortical areas during waking, resulting in increased activity in the slow‐waves range in that same area during subsequent NREM sleep. The second one consists of local states in
Tom Deboer
wiley   +1 more source

GLP‐1 at the Metabolic–Cognitive Interface: Reward, Affect, and Memory

open access: yesComprehensive Physiology, Volume 16, Issue 2, April 2026.
GLP‐1R signaling integrates metabolic state with neural circuits controlling reward, mood, and memory, acting as a metabolic‐cognitive interface. In reward pathways, it suppresses hedonic feeding and drug seeking; in affective circuits, sustained signaling promotes anxiolytic and antidepressant effects; and in the hippocampus, it enhances synaptic ...
Serena X. Gao   +5 more
wiley   +1 more source

Early‐Onset Hyperkinetic Movement Disorders Define the Most Severe Presentation of the ATP8A2‐Related Phenotypic Spectrum

open access: yesInternational Journal of Developmental Neuroscience, Volume 86, Issue 2, April 2026.
Our short communication establishes that the most severe, early‐onset presentation of ATP8A2 deficiency is a congenital encephalopathy hallmarked by prominent, nonprogressive hyperkinetic movement disorders. Moving beyond the historical CAMRQ4 ataxia classification is essential for the accurate diagnosis of this profound extrapyramidal phenotype ...
Fabio Bruschi   +5 more
wiley   +1 more source

Multicentre Evaluation of an AI‐Assisted Urine Test for Clinically Significant Prostate Cancer in Men Undergoing Initial Biopsy

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 4, April 2026.
ABSTRACT The Extracellular Vesicles Gene‐based Prostate Score (EGPS), powered by DeepSeek, is an artificial intelligence (AI) diagnostic tool that enhances the detection of clinically significant prostate cancer (csPCa) using urinary EV‐derived gene expression, without requiring digital rectal examination (DRE).
Shaoqin Jiang   +11 more
wiley   +1 more source

A phylogenetic classification of the Je language family. [PDF]

open access: yesOpen Res Eur
Ferraz Gerardi F   +4 more
europepmc   +1 more source

Malignant Potential of Temporal Bone Paragangliomas With Reference to GAPP System

open access: yesLaryngoscope Investigative Otolaryngology, Volume 11, Issue 2, April 2026.
ABSTRACT Objectives To evaluate the temporal bone paragangliomas (so‐called glomus tumors, TB‐PGLs) via the Grading System for Adrenal Pheochromocytoma and Paraganglioma (GAPP) and succinate dehydrogenase subunit B (SDHB) immunohistochemistry, and to discuss their implications for postoperative follow‐up and treatment strategies. Methods This report is
Noritaka Komune   +10 more
wiley   +1 more source

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