Results 31 to 40 of about 32,794 (269)

Prescribing pattern of anti-Parkinson drugs in Japan: a trend analysis from 2005 to 2010. [PDF]

open access: yesPLoS ONE, 2014
OBJECTIVE:Therapeutic options for Parkinson's disease mainly consist of L-dopa and dopamine agonists. However, in Japan, the product labeling of the ergot dopamine agonists, cabergoline and pergolide, was revised in April 2007 due to the risk of ...
Sachiko Nakaoka   +6 more
doaj   +1 more source

Validation of a New Sensitive Method for the Detection and Quantification of R and S-Epimers of Ergot Alkaloids in Canadian Spring Wheat Utilizing Deuterated Lysergic Acid Diethylamide as an Internal Standard

open access: yesToxins, 2021
Ergot sclerotia effect cereal crops intended for consumption. Ergot alkaloids within ergot sclerotia are assessed to ensure contamination is below safety standards established for human and animal health.
Jensen Cherewyk   +3 more
doaj   +1 more source

Pd-catalyzed enantioselective aerobic oxidation of secondary alcohols: Applications to the total synthesis of alkaloids [PDF]

open access: yes, 2008
Enantioselective syntheses of the alkaloids (-)-aurantioclavine, (+)-amurensinine, (-)-lobeline, and (-)- and (+)-sedamine are described. The syntheses demonstrate the effectiveness of the Pd-catalyzed asymmetric oxidation of secondary alcohols in ...
Bagdanoff, Jeffrey T.   +5 more
core   +2 more sources

Partial Reconstruction of the Ergot Alkaloid Pathway by Heterologous Gene Expression in Aspergillus nidulans

open access: yesToxins, 2013
Ergot alkaloids are pharmaceutically and agriculturally important secondary metabolites produced by several species of fungi. Ergot alkaloid pathways vary among different fungal lineages, but the pathway intermediate chanoclavine-I is evolutionarily ...
Daniel G. Panaccione   +2 more
doaj   +1 more source

Ergot Alkaloids on Cereals and Seeds: Analytical Methods, Occurrence, and Future Perspectives

open access: yesMolecules, 2023
Ergot alkaloids are secondary metabolites resulting from fungi of the genus Claviceps that have proven to be highly toxic. These mycotoxins commonly infect cereal crops such as wheat, rye, barley, and oats.
Ângela Silva   +3 more
doaj   +1 more source

Aptamer-based extraction of ergot alkaloids from ergot contaminated rye feed [PDF]

open access: yes, 2014
Ergot alkaloids are mycotoxins which can be found in food based on cereal-crops, due to a contamination of plants by fungi of the genus Claviceps. The ingestion of ergot contaminated cereal crops can lead to a severe poisoning known as ergotism. For food
Blust, Ronny   +7 more
core   +2 more sources

Fate of Ergot Alkaloids during Laboratory Scale Durum Processing and Pasta Production

open access: yesToxins, 2019
The fate of ergot alkaloids during the milling of durum and subsequent production and cooking of pasta was examined. Durum samples containing varying amounts of ergot sclerotia (0.01–0.1% by mass) were milled, and all milling product was analyzed ...
Sheryl A. Tittlemier   +5 more
doaj   +1 more source

Introduction to the Toxins Special Issue on Ergot Alkaloids

open access: yesToxins, 2015
Ergot alkaloids are among the most relevant natural products in the history of toxins and pharmaceuticals. Until the late 20th century, human and livestock exposure to ergot alkaloids was primarily through ingestion of “ergots,” which are spur-shaped or ...
Christopher L. Schardl
doaj   +1 more source

Ergot alkaloids contribute to virulence in an insect model of invasive aspergillosis

open access: yesScientific Reports, 2017
Neosartorya fumigata (Aspergillus fumigatus) is the most common cause of invasive aspergillosis, a frequently fatal lung disease primarily affecting immunocompromised individuals. This opportunistic fungal pathogen produces several classes of specialised
Daniel G. Panaccione   +1 more
doaj   +1 more source

Metabolic pathway of oligosaccharides in sorghum honeydew caused by Claviceps africana Rota metabólica de oligossacarídeos em exsudato da "doença açucarada" do sorgo causado por Claviceps africana

open access: yesCiência Rural, 2008
The occurrence of the alditol oligosaccharides in the Claviceps afriana honeydew is partly as a rational expression of the pathogen's selective nutritive metabolism of the sucrose supplied by the host plant. The experiments were carried out in laboratory
Amauri Bogo, Peter Mantle
doaj   +1 more source

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