Results 51 to 60 of about 13,168 (257)
Headache management for the pain specialist [PDF]
Headache is a common symptom caused by a wide variety of diseases. Primary headaches include migraine, cluster headache, tension-type headache and other less common diseases.
Ashkenazi, Avi, Silberstein, Stephen
core +2 more sources
Free radicals and oxidative damage caused by them have being suggested to be involved in the pathogenesis of migraine. These may result from distorted equilibrium of pro-oxidant/anti-oxidant system that continuously generates and detoxifies oxidants ...
Shahlaa H. Ali +2 more
doaj +3 more sources
Cyclopropanation of carbon-carbon double bonds in ring d of ergot alkaloids [PDF]
Some ergot alkaloid derivatives containing a double bond in ring D have been reacted with diazomethane/palladium diacetate reagent to result in formation of a fused cyclopropane ring.
Dörnyei, Gábor +5 more
core +1 more source
Report on the 2017 Proficiency Test of the European Union Reference Laboratory for Mycotoxins: determination of ergot alkaloids in rye [PDF]
Throughout history, there have been several deadly episodes of food poisoning by ergot alkaloids (EAs) (known as St. Anthony’s fire or ergotism). EAs are secondary metabolites produced by fungi of the Claviceps genus (chiefly Claviceps purpurea), which ...
BOUTEN KATRIEN +4 more
core +2 more sources
Objectives The aim of this study is to generate hypotheses about unknown drugs associated with the onset or worsening of Raynaud's Phenomenon (RP) and to explore their potential pathophysiological mechanisms through a mixed disproportionality/clustering analysis from the WHO pharmacovigilance database.
Alex Hlavaty +4 more
wiley +1 more source
Migraine: Diagnosis, treatment and understanding c1960-2010 [PDF]
seminar transcriptThere are around eight million migraine sufferers in the UK today. This Witness Seminar looked at the last 50 years of research into the diagnosis and treatment of the condition and the changing attitudes of the medical profession ...
Overy, C, Tansey, EM
core
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
Psychedelic drugs have seen a resurgence in interest as a next generation of psychiatric medicines with potential as rapid‐acting antidepressants (RAADs). Despite promising early clinical trials, the mechanisms which underlie the effects of psychedelics are poorly understood.
Laith Alexander +5 more
wiley +1 more source
Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy
Conventional approaches for antiparasitic drug discovery center upon discovering selective agents that adversely impact parasites with minimal host side effects.
John D Chan +2 more
doaj +1 more source
Ergotamine intoxication and ARF
Carlos Hiza Cremona +4 more
doaj +1 more source
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley +1 more source

