Results 101 to 110 of about 439 (114)

Ergovaline-induced vasoconstriction in an isolated bovine lateral saphenous vein bioassay1

Journal of Animal Science, 2007
Ergovaline has been proposed as a toxic component of endophyte-infected tall fescue. As many of the symptoms of fescue toxicosis are a result of compromised circulation, the objective of this study was to examine the vasoconstrictive potentials of ergovaline and a more documented ergopeptine, ergotamine, using a bovine, lateral (cranial branch ...
B. C. Arrington, Darrin L. Smith, Lowell P. Bush, James L. Klotz, Wilson D. Shafer, L. L. Smith, J. R. Strickland   +6 more
openaire   +3 more sources

Ergovaline does not alter the severity of ryegrass staggers induced by lolitrem B

New Zealand Veterinary Journal, 2018
To investigate a possible interaction between lolitrem B and ergovaline by comparing the incidence and severity of ryegrass staggers in sheep grazing ryegrass (Lolium perenne) containing lolitrem B or ryegrass containing both lolitrem B and ergovaline.Ninety lambs, aged approximately 6 months, were grazed on plots of perennial ryegrass infected with ...
SC Finch, JB Vlaming, BL Sutherland, C van Koten, WJ Mace, LR Fletcher   +5 more
openaire   +3 more sources

Ruminal tryptophan-utilizing bacteria degrade ergovaline from tall fescue seed extract

Journal of Animal Science, 2017
The objectives of this study were to evaluate degradation of ergovaline in a tall fescue [ (Schreb.) Darbysh.] seed extract by rumen microbiota ex vivo and to identify specific bacteria capable of ergovaline degradation in vitro. Rumen cell suspensions were prepared by harvesting rumen fluid from fistulated wether goats ( = 3), straining, and ...
Michael D. Flythe, Glen E. Aiken, Brittany E. Harlow, Jack P. Goodman, Huihua Ji, Bert C. Lynn   +5 more
openaire   +3 more sources

Ergovaline occurrence in grasses infected by fungal endophytes of semi‐arid pastures in Spain

Journal of the Science of Food and Agriculture, 2003
AbstractErgovaline is a mycotoxin produced by fungal endophytes belonging to Neotyphodium and Epichloë spp in several host grass species. Owing to the production of this alkaloid, the ingestion of endophyte‐infected grasses causes toxicosis in grazing animals.
Beatriz R. Vázquez de Aldana, Balbino García Criado, Antonia García Ciudad, Iñigo Zabalgogeazcoa   +3 more
openaire   +2 more sources

Cardiovascular, respiratory, and body temperature responses of sheep to the ergopeptides ergotamine and ergovaline

American Journal of Veterinary Research, 2002
AbstractObjective—To compare the effects of the ergot alkaloid ergovaline with effects of ergotamine on blood pressure, heart rate, respiratory rate, and body temperature in conscious sheep.Animals—3 sheep with indwelling arterial catheters.Procedure—Ergotamine and ergovaline were injected IV (20 nmol/kg), and their effects on arterial blood pressure ...
Gordon W. Reynolds, Lance M. McLeay, Barry L. Smith   +2 more
openaire   +3 more sources

Herbage Mass, Nutritive Value, and Ergovaline Concentration of Stockpiled Tall Fescue

Crop Science, 2003
Tall fescue (Festuca arundinacea Schreb.) infected with an endophyte that does not produce ergot‐like alkaloids (nontoxic endophyte) has not been evaluated for herbage mass, nutritive value, and ergovaline concentration when stockpiled during winter. Our objective was to quantify these responses for tall fescue infected with a native endophyte (K31 E+),
Robert L. Kallenbach, George E. Rottinghaus, Charles P. West, Greg Bishop-Hurley, M. D. Massie   +4 more
openaire   +2 more sources

ERGOVALINE TOXICITY ON CACO-2 CELLS AS ASSESSED BY MTT, ALAMARBLUE, AND DNA ASSAY

In Vitro Cellular and Developmental Biology-Animal, 2003
The exact mechanisms of fescue toxicity in animals have yet to be established, but it has been associated with an inability to thrive. Ergovaline is the major ergopeptine alkaloid associated with fungal infections of tall fescue. Gastrointestinal (GI) toxicity of ergovaline (10(-11) to 10(-4) M) was evaluated in Caco-2 cells (mimicking the GI ...
openaire   +3 more sources

Simplified Extraction of Ergovaline and Peramine for Analysis of Tissue Distribution in Endophyte-Infected Grass Tillers

Journal of Agricultural and Food Chemistry, 2002
An improved extraction and cleanup procedure for quantitative analysis of ergovaline in Neotyphodium-infected grass tissues by high-performance liquid chromatography was developed, utilizing aqueous 2-propanol-lactic acid as extraction solvent. Losses of sample material and time requirements were significantly reduced, handling procedures simplified ...
Jan Schmid, Elizabeth Davies, Brian Anthony Tapper, Geoffrey A. Lane, Martin J. Spiering   +4 more
openaire   +3 more sources

DETERMINATION OF ERGOVALINE IN ENDOPHYTED SEEDS BY HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY (HPTLC)

Journal of Liquid Chromatography & Related Technologies, 2000
High performance thin layer chromatography (HPTLC) is used to rapidly determine the presence and amount of ergovalin in seeds of Graminaceae infested with Neotyphodium Coenophialum. Quinine is used as an internal standard. The mycotoxin is solubilized under acid conditions and extracted with chloroform under alkaline conditions.
Videmann, B., Bony, Sylvie, Berny, Philippe   +2 more
openaire   +4 more sources

Improved Method of Analysis for Ergovaline in Tall Fescue by High-Performance Liquid Chromatography

Journal of Agricultural and Food Chemistry, 1997
A rapid HPLC method of analysis for ergovaline in tall fescue plants is presented; it offers the advantages of utilizing readily available materials that are safer to use than those in previous methods. In addition, the sample preparation and chromatographic method allow for the detection and quantification of both C-8 epimers of the target alkaloid ...
Miroslav Flieger, Richard A. Shelby
openaire   +2 more sources