Results 31 to 40 of about 231,975 (269)

Formation of litter crusts and its multifunctional ecological effects in a desert ecosystem

open access: yesEcosphere, 2018
Desertification is one of the major issues in global environmental change, and it is of great concern to scientists and policy‐makers in the world. Litter crusts can be of great importance for the restoration and management of desert ecosystems.
Chao Jia   +7 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso   +5 more
wiley   +1 more source

An outer membrane vesicle‐associated two‐track model for enterotoxigenic Bacteroides fragilis oncogenesis

open access: yesMolecular Oncology, EarlyView.
Enterotoxigenic Bacteroides fragilis is a gut bacterium linked to bowel cancer. We propose that its toxin acts along two routes: at the cell surface, cutting the adhesion protein E‐cadherin and triggering inflammation; and inside the cell, delivered by bacterial vesicles, switching on NOD1 and cancer stem cell programs.
Kangchan Choi   +2 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

open access: yesFEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Fluorination: A strategy to tune the interactions of molecules and nanoscale systems with biological matter

open access: yesFEBS Open Bio, EarlyView.
This minireview explores fluorination as a key strategy to optimize therapeutic molecules and nanocarriers. By incorporating different fluorinated motifs—from single atoms to linear and branched chains—drug delivery, cellular uptake, and colloidal stability can be improved and fine‐tuned.
Martina Beccalli   +2 more
wiley   +1 more source

Sediment flow paths and associated organic carbon dynamics across a Mediterranean catchment [PDF]

open access: yesHydrology and Earth System Sciences, 2015
Terrestrial sedimentation buries large amounts of organic carbon (OC) annually, contributing to the terrestrial carbon sink. The temporal significance of this sink will strongly depend on the attributes of the depositional environment, but also on the ...
C. Boix-Fayos   +5 more
doaj   +1 more source

Effect of Activated Water Irrigation on the Yield and Water Use Efficiency of Winter Wheat under Irrigation Deficit

open access: yesAgronomy, 2022
Activated water irrigation has been widely investigated as an effective production increasing measure. However, the response of activated water irrigation in plant growth and water use efficiency (WUE) with the irrigation amount is not well understood ...
Huan Wang, Jun Fan, Wei Fu
doaj   +1 more source

Erosion and Erosion-Corrosion

open access: yesZairyo-to-Kankyo, 2008
エロージョン・コロージョン現象の複雑な発生機構と紛らわしい用語の定義のために,発電所の配管部に時として発生する「エロージョン・コロージョン」を理解することは非常に難しい.最近,エロージョン・コロージョンの代わりに,FAC (流れによって加速される腐食) という言葉が,発電所に用いられる配管材料の減肉現象として紹介されている.しかしながら,FACは必ずしも良く理解されていないし,エロージョン・コロージョンとも比較がなされていない.そこで,本稿ではエロージョン,エロージョン・コロージョンおよびFAC現象の理解を深め,再確認をするために,まず,エロージョンおよびエロージョン・コロージョンの起源,定義およびこれまでの基礎的な見解についてまとめた.次に,流速と環境の腐食性を軸にし,エロージョン ...
openaire   +2 more sources

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