Results 51 to 60 of about 436,372 (316)

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Government and agency response to soil erosion risk in europe [PDF]

, 2007
Provides an assessment of soil erosion throughout Europe, an important aspect to control and manage if landscapes are to be sustained for the future. This book focuses on issues of: area specific soil erosion rates, on and off-site impacts, government ...
Castillo, Victor, Ritsema, Coen, Arnalds, Andres, Bazzoffi, Paulo, Fullen, Michael A., Booth, Colin A., Martin, Philippe   +6 more
core  

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source

Influence of sediment trapping in reservoirs on runoff and sediment discharge variations in Yangtze River

Shui kexue jinzhan, 2014
In order to understand the influence of reservoir construction on the runoff and sediment discharge variations,relationships between water and sediment parameters and reservoir capacity parameters in the trunk stream and tributaries of the Yangtze River ...
WANG Yangui, SHI Hongling, LIU Xi
doaj   +1 more source

Mapping erosion-corrosion of carbon steel in oil exploration conditions : some new approaches to characterizing mechanisms and synergies

, 2010
Erosion by solid particles in oil/water slurries is a technologically important area. In such conditions, it is necessary to distinguish between the effects of the sand, aqueous environment, and the oil.
Abdulrahmen, G.H., Stack, M.M.
core   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Technical note: Isotopic fractionation of evaporating waters: effect of sub-daily atmospheric variations and eventual depletion of heavy isotopes [PDF]

Hydrology and Earth System Sciences
Isotopic fractionation of evaporating waters has been studied constantly in recent decades, particularly because it enables calculation of both the volume of water evaporated from a water body and the isotopic composition of its source water.
F. Gallart, S. González-Fuentes, P. Llorens   +2 more
doaj   +1 more source

Erosive arthritis [PDF]

Arthritis Research & Therapy, 2007
Inflammation and degradation of bone are two closely linked processes. Chronic inflammatory arthritis not only leads to inflammatory bone loss but it also involves local erosion of articular bone. This osteo-destructive feature of chronic inflammatory arthritis is a major cause of disability in patients with rheumatoid arthritis.
openaire   +2 more sources

Soil erosion in an avalanche release site (Valle d'Aosta: Italy): towards a winter factor for RUSLE in the Alps [PDF]

, 2014
Soil erosion in Alpine areas is mainly related to extreme topographic and weather conditions. Although different methods of assessing soil erosion exist, the knowledge of erosive forces of the snow cover needs more investigation in order to allow soil ...
Maggioni, M., C. Alewell, Maggioni, Margherita, Freppaz, M., E. Ceaglio, Stanchi, Silvia, S. Stanchi, Freppaz, Michele, M. Maggioni, Meusburger, K., Alewell, C., M. Freppaz, K. Meusburger, E. Zanini, Zanini, E., Zanini, Ermanno, Stanchi, S., Ceaglio, E.   +17 more
core   +1 more source

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source