Results 41 to 50 of about 643,576 (312)

A model for fluvial bedrock incision by impacting suspended and bed load sediment [PDF]

, 2008
A mechanistic model is derived for the rate of fluvial erosion into bedrock by abrasion from uniform size particles that impact the bed during transport in both bed and suspended load.
Dietrich, William E., Lamb, Michael P., Sklar, Leonard S.   +2 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Microstructural Insights into Solid Particle Erosion in a High-Chromium Cast Iron

Metals
Solid particle erosion (SPE) significantly limits the service life of High-Chromium Cast Irons (HCCIs), widely used in power generation and mining industries.
Alessio Suman, Annalisa Fortini, Nicola Zanini   +2 more
doaj   +1 more source

Effect of Atomic Oxygen on Electric Properties of Graphene Films

Cailiao gongcheng, 2017
The resistance and the surface morphology of the graphene films were studied after atomic oxygen exposure. The graphene films can be etched away during atomic oxygen exposure, the resistance of graphene films decreases at first and then increases.
LIU Yu-ming, LI Man, LIU Xiang-peng, ZHANG Kai, ZHAO Chun-qing   +4 more
doaj   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Research on New Numerical Simulation Method of Erosion Rate of High Pressure Manifold

Shiyou jixie, 2021
At present, the calculation of erosion rate is mainly based on semi-empirical calculation models. The prediction results of the models are not very accurate.
Li Jianting, Zeng Yun, Li Ning
doaj  

Lateral Marsh Edge Erosion as a Source of Sediments for Vertical Marsh Accretion [PDF]

, 2018
With sea level rise accelerating and sediment inputs to the coast declining worldwide, there is concern that tidal wetlands will drown. To better understand this concern, sources of sediment contributing to marsh elevation gain were computed for Plum ...
Barbier, Bauer, Blum, Blum, Cahoon, Cavatorta, Claessens, Cook, Costanza, Day, Day, Dhillon, Donnelly, Donnelly, Engelhart, Eyre, Fagherazzi, Fagherazzi, Foley, Forbrich, French, Ganju, Ganju, Geyer, Gittman, Gosselink, Hayden, Hein, Hobbs, Hopkinson, Hughes, Kirwan, Kirwan, Kirwan, Koch, Lane, Leonardi, Leonardi, Leonardi, Levin, Magirl, Marcus, Mariotti, Mariotti, Mariotti, Mattheus, McGeehin, McKee, Meade, Meade, Megonigal, Millette, Milliman, Mineau, Morris, Morris, Morris, Morris, Morris, Mudd, Pasternack, Pavich, Priestas, Rahmstorf, Raymond, Redfield, Redfield, Redfield, Reed, Rovere, Schmidt, Schwimmer, Sholkovitz, Stuiver, Swales, Syvitski, Townsend, Trimble, Vallino, Vallino, Walsh, Warrick, Warrick, Watson, Weston, Wilson, Wollheim, Wollheim, Worm, Yarbro, Zhao   +90 more
core   +3 more sources

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Erosion Factor Analysis of Coiled Tubing with Helical Buckling

Shiyou jixie, 2023
During coiled tubing(CT)operations,a wide annulus between CT and casing may lead to helical buckling and serious erosion of the CT inner wall.The inner wall erosion of CT with helical buckling was investigated through physical experiment and numerical ...
Cao Yinping, Chen Zetian, Dou Yihua, Zheng Jie, Kang Zhaofei   +4 more
doaj