Results 51 to 60 of about 5,593 (170)
ObjectiveGastroesophageal reflux disease (GERD) is associated with bothersome symptoms and neoplastic progression into Barrett's esophagus and esophageal adenocarcinoma.
Yen-Wen Wu +9 more
doaj +1 more source
Abstract Background Surgical fundoplication is the standard treatment for refractory gastroesophageal reflux disease (GERD) with large (≥3 cm) hiatal hernias; however, its invasiveness is problematic in older adults and high‐risk patients. Anti‐reflux mucosal intervention (ARMI) is a less invasive endoscopic alternative; however, patients with large ...
Masachika Saino +12 more
wiley +1 more source
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim +4 more
wiley +1 more source
Morphological Diagnosis of Erosive Esophagitis in Patients with Gastroesophageal Reflux Disease
The esophageal biopsies of 79 patients with clinical evidence of gastroesophageal reflux disease were examined. Using computer morphometry the intercellular spaces of the squamous epithelium were measured and analyzed along with the features of ...
Yu.A. Haidar +2 more
doaj +1 more source
ABSTRACT A 13‐year‐old girl presented with 4 months of recurrent projectile vomiting and weight loss without diarrhea. Investigations confirmed hypochloraemic metabolic alkalosis, strongly positive coeliac serology, nutritional deficiency, and biopsy‐proven Marsh–Oberhuber Grade 3C total villous atrophy.
Rahman Syed +7 more
wiley +1 more source
Background. Insulin resistance is the core of Metabolic Syndrome which carries a high risk for cardiovascular events. Insulin resistance had been reported to be higher in GERD patients than subjects without GERD, specifically in erosive esophagitis ...
Laras Budiyani +3 more
doaj
The role of dexlansoprazole modified-release in the management of gastroesophageal reflux disease
Dexlansoprazole modified-release (MR) is the R-enantiomer of lansoprazole and is currently the only proton-pump inhibitor (PPI) with a novel dual delayed release (DDR) formulation. Overall, dexlansoprazole MR demonstrates a similar safety and side-effect
Ronnie Fass, Rosita Frazier
doaj +1 more source
Different risk factors between reflux symptoms and mucosal injury in gastroesophageal reflux disease
Gastroesophageal reflux disease (GERD) is diagnosed based on typical symptoms in clinical practice. It can be divided into two groups using endoscopy: erosive and nonerosive reflux disease (NERD).
Chung-Hsien Li +6 more
doaj +1 more source
In 123 patients with inconclusive esophagogastric junction outflow obstruction, 4D EGJ‐DI and diameter differed significantly across FLIP and TBE groups and reliably discriminated normal from reduced EGJ opening on FLIP. ABSTRACT Background Esophagogastric junction outflow obstruction (EGJOO) identified on high‐resolution manometry (HRM) remains a ...
Aidan D. Smires +7 more
wiley +1 more source

