Results 51 to 60 of about 5,593 (170)

Association of esophageal inflammation, obesity and gastroesophageal reflux disease: from FDG PET/CT perspective.

open access: yesPLoS ONE, 2014
ObjectiveGastroesophageal reflux disease (GERD) is associated with bothersome symptoms and neoplastic progression into Barrett's esophagus and esophageal adenocarcinoma.
Yen-Wen Wu   +9 more
doaj   +1 more source

Clinical Utility of Anti‐reflux Mucosal Intervention for Refractory Gastroesophageal Reflux Disease in Patients With a Hiatal Hernia

open access: yesDEN Open, Volume 7, Issue 1, April 2027.
Abstract Background Surgical fundoplication is the standard treatment for refractory gastroesophageal reflux disease (GERD) with large (≥3 cm) hiatal hernias; however, its invasiveness is problematic in older adults and high‐risk patients. Anti‐reflux mucosal intervention (ARMI) is a less invasive endoscopic alternative; however, patients with large ...
Masachika Saino   +12 more
wiley   +1 more source

Comparative Pharmacokinetics and Safety of Orally Disintegrating and Conventional Tablet Formulations of Zastaprazan in Healthy Subjects

open access: yesPharmacology Research &Perspectives, Volume 14, Issue 6, December 2026.
ABSTRACT Zastaprazan, a potassium‐competitive acid blocker, has been developed as an orally disintegrating tablet (ODT) to improve administration flexibility. This study evaluated the pharmacokinetics and safety of a single 20 mg dose of Zastaprazan ODT administered with or without water compared with the conventional tablet in healthy volunteers.
Hyung‐Gun Kim   +4 more
wiley   +1 more source

Morphological Diagnosis of Erosive Esophagitis in Patients with Gastroesophageal Reflux Disease

open access: yesGastroenterologìa, 2016
The esophageal biopsies of 79 patients with clinical evidence of gastroesophageal reflux disease were examined. Using computer morphometry the intercellular spaces of the squamous epithelium were measured and analyzed along with the features of ...
Yu.A. Haidar   +2 more
doaj   +1 more source

Recurrent Projectile Vomiting as the Sole Presenting Feature of Coeliac Disease With Marsh–Oberhuber Grade 3C Enteropathy in a 13‐Year‐Old Girl: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 10, October 2026.
ABSTRACT A 13‐year‐old girl presented with 4 months of recurrent projectile vomiting and weight loss without diarrhea. Investigations confirmed hypochloraemic metabolic alkalosis, strongly positive coeliac serology, nutritional deficiency, and biopsy‐proven Marsh–Oberhuber Grade 3C total villous atrophy.
Rahman Syed   +7 more
wiley   +1 more source

Differences in the Insulin Resistance Levels Measured by HOMA-IR between Patients with Erosive and Non-Erosive Gastroesophageal Reflux Disease

open access: yesJournal of the ASEAN Federation of Endocrine Societies, 2017
Background. Insulin resistance is the core of Metabolic Syndrome which carries a high risk for cardiovascular events. Insulin resistance had been reported to be higher in GERD patients than subjects without GERD, specifically in erosive esophagitis ...
Laras Budiyani   +3 more
doaj  

The role of dexlansoprazole modified-release in the management of gastroesophageal reflux disease

open access: yesTherapeutic Advances in Gastroenterology, 2017
Dexlansoprazole modified-release (MR) is the R-enantiomer of lansoprazole and is currently the only proton-pump inhibitor (PPI) with a novel dual delayed release (DDR) formulation. Overall, dexlansoprazole MR demonstrates a similar safety and side-effect
Ronnie Fass, Rosita Frazier
doaj   +1 more source

Different risk factors between reflux symptoms and mucosal injury in gastroesophageal reflux disease

open access: yesKaohsiung Journal of Medical Sciences, 2015
Gastroesophageal reflux disease (GERD) is diagnosed based on typical symptoms in clinical practice. It can be divided into two groups using endoscopy: erosive and nonerosive reflux disease (NERD).
Chung-Hsien Li   +6 more
doaj   +1 more source

Laparoscopic Modified One Anastomosis Gastric Bypass for Severe Obesity After Pancreaticoduodenectomy: A Safe Approach to the Hostile Abdomen, a First Case Report

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Chih‐Kun Huang   +3 more
wiley   +1 more source

Biomechanical Assessment During High‐Resolution Impedance Manometry Enhances Characterization of Inconclusive Esophagogastric Junction Outflow Obstruction

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 10, October 2026.
In 123 patients with inconclusive esophagogastric junction outflow obstruction, 4D EGJ‐DI and diameter differed significantly across FLIP and TBE groups and reliably discriminated normal from reduced EGJ opening on FLIP. ABSTRACT Background Esophagogastric junction outflow obstruction (EGJOO) identified on high‐resolution manometry (HRM) remains a ...
Aidan D. Smires   +7 more
wiley   +1 more source

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