Results 21 to 30 of about 2,494 (287)

Conventional Pig as Animal Model for Human Renal Drug Excretion Processes: Unravelling the Porcine Renal Function by Use of a Cocktail of Exogenous Markers

Frontiers in Pharmacology, 2020
Over recent years, pigs have been promoted as potential animal model due to their anatomical and physiological similarities with humans. However, information about the contribution of distinct renal elimination processes [glomerular filtration rate (GFR),
Laura Dhondt, Siska Croubels, Peter De Paepe, Steven C. Wallis, Saurabh Pandey, Jason A. Roberts, Jason A. Roberts, Jason A. Roberts, Jason A. Roberts, Jason A. Roberts, Jeffrey Lipman, Jeffrey Lipman, Jeffrey Lipman, Pieter De Cock, Pieter De Cock, Pieter De Cock, Mathias Devreese   +16 more
doaj   +1 more source

Assessing the kidney function parameters glomerular filtration rate and effective renal plasma flow with dynamic FDG-PET/MRI in healthy subjects

EJNMMI Research, 2018
Background A method was developed to assess the kidney parameters glomerular filtration rate (GFR) and effective renal plasma flow (ERPF) from 2-deoxy-2-[18F]fluoro-d-glucose (FDG) concentration behavior in kidneys, measured with positron emission ...
Barbara K. Geist, Pascal Baltzer, Barbara Fueger, Martina Hamboeck, Thomas Nakuz, Laszlo Papp, Sazan Rasul, Lalith Kumar Shiyam Sundar, Marcus Hacker, Anton Staudenherz   +9 more
doaj   +1 more source

Estimation of renal perfusion based on measurement of rubidium-82 clearance by PET/CT scanning in healthy subjects

EJNMMI Physics, 2021
Background Changes in renal blood flow (RBF) may play a pathophysiological role in hypertension and kidney disease. However, RBF determination in humans has proven difficult.
Stine Sundgaard Langaa, Thomas Guldager Lauridsen, Frank Holden Mose, Claire Anne Fynbo, Jørn Theil, Jesper Nørgaard Bech   +5 more
doaj   +1 more source

Associations of Smoking with Alterations in Renal Hemodynamics May Depend on Sex- Investigations in Potential Kidney Donors

Kidney & Blood Pressure Research, 2013
Background/Aims: Cigarette smoking is a risk factor for renal damage, but little is known about subclinical effects of smoking on renal hemodynamics and parameters of renal function in humans.
Hana Guberina, Marcus Baumann, Heike Bruck, Thorsten Feldkamp, Jens Nürnberger, Andreas Kribben, Thomas Philipp, Oliver Witzke, Georgios Sotiropoulos, Anna Mitchell   +9 more
doaj   +1 more source

Evaluation of feline renal perfusion with contrast-enhanced ultrasonography and scintigraphy [PDF]

, 2016
Contrast-enhanced ultrasound (CEUS) is an emerging technique to evaluate tissue perfusion. Promising results have been obtained in the evaluation of renal perfusion in health and disease, both in human and veterinary medicine. Renal scintigraphy using Tc-
Bosmans, Tim, Dobbeleir, André, Duchateau, Luc, Hesta, Myriam, Lybaert, Lien, Peremans, Kathelijne, Saunders, Jimmy, Stock, Emmelie, Vandermeulen, Eva, Vanderperren, Katrien   +9 more
core   +4 more sources

177Lu-DOTATATE peptide receptor radionuclide therapy in patients with borderline low and discordant renal parameters: Treatment feasibility assessment by sequential estimation of triple parameters and filtration fraction

World Journal of Nuclear Medicine, 2018
The aim was to assess the effect of standard fixed-dose protocol of 177Lu-DOTATATE peptide receptor radionuclide therapy (PRRT) in patients with borderline low renal function of one parameter (glomerular filtration rate [GFR], effective renal plasma flow
Chinna Naik, Sandip Basu
doaj   +1 more source

A Systematic Review of Renal Functional Reserve in Adult Living Kidney Donors

Kidney International Reports, 2020
Introduction: The kidney’s capacity to increase its glomerular filtration rate (GFR) in response to a higher functional demand is known as the renal functional reserve (RFR).
Andreja Figurek, Valerie A. Luyckx, Thomas F. Mueller   +2 more
doaj   +1 more source

The correlation between preoperative renal scintigraphy and postoperative renal function in upper urinary tract urothelial carcinoma patients following radical nephroureterectomy

Urological Science, 2017
Objective: To predict the renal function after nephroureterectomy (NUR) for upper urinary tract urothelial cancer (UTUC) based on preoperative technetium-99m mercaptoacetyltriglycine (99mTc-MAG3) renal scintigraphy.
Chan-Jung Liu, Wen-Horng Yang, Chien-Hui Ou   +2 more
doaj   +1 more source

Kidney Dysfunction in Adult Offspring Exposed In Utero to Type 1 Diabetes Is Associated with Alterations in Genome-Wide DNA Methylation. [PDF]

PLoS ONE, 2015
Fetal exposure to hyperglycemia impacts negatively kidney development and function.Our objective was to determine whether fetal exposure to moderate hyperglycemia is associated with epigenetic alterations in DNA methylation in peripheral blood cells and ...
Jean-François Gautier, Raphaël Porcher, Charbel Abi Khalil, Naima Bellili-Munoz, Lila Sabrina Fetita, Florence Travert, Simeon-Pierre Choukem, Jean-Pierre Riveline, Samy Hadjadj, Etienne Larger, Philippe Boudou, Bertrand Blondeau, Ronan Roussel, Pascal Ferré, Eric Ravussin, François Rouzet, Michel Marre   +16 more
doaj   +1 more source

Evaluation of Renal Function Under Controlled Hypotension in Zero Ischemia Robotic Assisted Partial Nephrectomy

Kidney & Blood Pressure Research, 2014
Background/Aims: In partial nephrectomy with hilar clamping every minute of ischemia can impair renal function, thus great importance is having the controlled hypotension as a part of zero ischemia technique.
Ester Forastiere, Claudia Claroni, Maria Sofra, Giulia Torregiani, Marco Covotta, Maria Grazia Marchione, Diana Giannarelli, Rocco Papalia   +7 more
doaj   +1 more source