Results 101 to 110 of about 2,825,138 (268)
Філософія освітиThe article is dedicated to the philosophical analysis of the term “bullshit”, which was systematically conceptualized by the American philosopher Harry G.
Михайло Бойченко +1 more
doaj +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Verdad, error y aprendizaje infantil en el pensamiento de A. Rosmini
Revista Española de PedagogíaLa verdad es un valor en cualquier forma que la tome, incluso si la mentira y la corrupción son frecuentes en nuestra sociedad. Sin embargo, después de los estudios de Piaget, a la Pedagogía del Error le gusta estar en creciente evaluación.
W.R. Darós
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Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
LANDING QUALITY IN ARTISTIC GYMNASTICS IS RELATED TO LANDING SYMMETRY
Biology of Sport, 2013 In gymnastics every exercise finishes with a landing. The quality of landing depends on subjective (e.g. biomechanical) and objective (e.g. mechanical characteristics of landing area) factors. The aim of our research was to determine which biomechanical (
Ivan Čuk, Miha Marinšek
doaj
Australasian Journal of Philosophy, 2008 Moral error theory of the kind defended by J. L. Mackie and Richard Joyce is premised on two claims: (1) that moral judgements essentially presuppose that moral value has absolute authority, and (2) that this presupposition is false, because nothing has absolute authority. This paper accepts (2) but rejects (1).
openaire +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Nauka ta progres transportu, 2008 In the article the influence of resistance of secondary winding of the high-voltage measuring current transformer on the error of device of its compensation is considered.
N. V. Rudevych
doaj
Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source