Results 81 to 90 of about 2,825,138 (268)
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Even though, in Mahyna Buddhism, ultimate reality is sometimes considered to have a conscious nature, the most common Buddhist approach to consciousness is rather a phenomenal one.
Ovidiu Cristian Nedu
doaj +1 more source
Typical Lexical Errors in Russian Speech of Greek Students (Level A2)
Different approaches to the interpretation of the concept “error in speech in a non-native language” are analyzed: psychological, psycholinguistic, linguistic, methodical.
N. L. Fedotova, (. Z. Stamboleva
doaj +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
English Language Error Analysis of the Written Texts Produced by Ukrainian Learners: Data Collection
English Language Error Analysis of the Written Texts Produced by Ukrainian Learners: Data Collection Recently, the studies of second language acquisition have tended to focus on learners errors as they help to predict the difficulties involved in ...
Lessia Mykolayivna Kotsyuk
doaj +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
It is well known that a center of a given circle cannot be constructed using only a straightedge and that this was proven by David Hilbert. Still it is not so clear what kind of object is proven to be non-existing. We analyze different attempts to define a geometric construction appearing in the literature and observe that none of them is really ...
openaire +3 more sources

